Publisher Summary Although apoptosis can be induced by a number of stimuli, it has
become apparent that there are common connecting themes linking the diverse systems …

Fas (CD95/Apo-1) gene expression is dysregulated in a number of diseased states.
Towards understanding the regulation of fas gene expression, we previously identified …

Apoptosis (programmed cell death) is a central protective response to excess oxidative
damage (especially DNA damage), and is also essential to embryogenesis. morphogenesis …

The occurrence of physiological cell death has been known for decades, but interest in the
subject was renewed in 1972 when Kerr, Wyllie and Currie described in detail the …

The epidermal keratinocyte stem cell is distinguished by a relatively undifferentiated
phenotype and an ability to proliferate. As part of a carefully orchestrated process, the …

Publisher Summary This chapter focuses on the current state of knowledge regarding the
mechanisms by which programmed cell death (PCD) is triggered by cancer …

Adrenoreceptor agonists induce a hypertrophic phenotype in vitro and in vivo. To investigate
the molecular remodeling in chronic cardiac hypertrophy we infused adult male mice with …

Although cell death has long been recognized to be a significant element in the process of
embryonic morphogenesis, its relationships to differentiation and its mechanisms are only …

The transcription factor activator protein‐1 (AP‐1) is activated in response to physiological
activity in neuronal circuits and in response to neuronal injury associated with various acute …

The last decade has seen the rapid development of research investigating the molecular
mechanisms whereby hormones, peptide growth factors and cytokines regulate cell …