Hyperuricemia with consequent monosodium urate crystal deposition leads to gout,
characterized by painful, incapacitating inflammatory arthritis flares that are also associated …

Gut microbiota is an important modulator of human health and contributes to high inter-
individual variation in response to food and pharmaceutical ingredients. The clinical …

The incidence of hyperuricemia and gout has been increasing year by year, and it is
showing a younger trend. However, the first-line drugs currently used for hyperuricemia and …

Introduction Gout arthritis (GA) is an intermittent inflammatory disease affecting
approximately 10% of the worldwide population. Symptomatic phases (acute flares) are …

Both inosine and guanosine are precursors of uric acid that may cause the diseases of
hyperuricemia and gout in humans. Here, a promising bacterial strain for efficiently …

Hyperuricemia (HUA) is a metabolic syndrome caused by abnormal purine metabolism.
Although recent studies have noted a relationship between the gut microbiota and gout …

Epigallocatechin gallate (EGCG), a prominent bioactive compound found in tea, offers
numerous health benefits. Previous studies have highlighted its potential in mitigating …

Introduction It is estimated that 90% of hyperuricemia cases are attributed to the inability to
excrete uric acid (UA). The two main organs in charge of excreting UA are the kidney (70%) …

Phellinus igniarius is an important medicinal and edible fungus with diverse biological
activities. This study aimed to investigate the effects of aqueous extract from P. igniarius …

Hyperuricemia is a prevalent metabolic disorder that arises from abnormal purine
metabolism and reduced excretion of uric acid (UA). The gut microbiota plays a significant …