Despite advances in neurosurgical techniques and radio-/chemotherapy, the treatment of
brain tumors remains a challenge. This is particularly true for the most frequent and fatal …

Oxidative stress refers to the imbalance between oxidation and antioxidant activity in the
body. Oxygen is reduced by electrons as part of normal metabolism leading to the formation …

Background. Cancer-associated fibroblasts (CAFs) within the tumor microenvironment are
key players in tumorigenesis and tumor development. Nevertheless, the regulatory …

Abstract Nuclear protein-1 (NUPR1), located on chromosome 16p11. 2, is a stress response
factor that plays an important role in the growth and migration of human malignant tumor …

Medicinal herbal plants have been commonly used for intervention in different diseases and
improvement of health worldwide. Koumine, an alkaloid monomer found abundantly in …

Rafoxanide is commonly used as anti-helminthic medicine in veterinary medicine, a main
compound of salicylanilide. Previous studies have reported that rafoxanide, as an inhibitor of …

Results Upon H 2 O 2 treatment, cell viability was significantly decreased, while THSG
clearly attenuated this decrease in a dose-dependent manner. Compared with the negative …

Oxidative stress has currently been proposed as a risk factor associated with the
development and proression of osteoporosis. In this study, we identify the effect of …

Malignant glioma remains the most frequent form of primary brain tumors all over the world.
The gliomagenesis is characterized by various molecular processes such as neoplastic …

Objective The objective was to further investigate apoptosis induction by Babao Dan (BBD),
which supports its anti-tumor mechanisms, using two human gastric cancer cell lines (AGS …