[HTML][HTML] Abscisic acid as pathogen effector and immune regulator

L Lievens, J Pollier, A Goossens, R Beyaert… - Frontiers in plant …, 2017 - frontiersin.org
Abscisic acid (ABA) is a sesquiterpene signaling molecule produced in all kingdoms of life.
To date, the best known functions of ABA are derived from its role as a major phytohormone …

[HTML][HTML] Abscisic acid: a novel nutraceutical for glycemic control

E Zocchi, R Hontecillas, A Leber, A Einerhand… - Frontiers in …, 2017 - frontiersin.org
Abscisic acid is naturally present in fruits and vegetables, and it plays an important role in
managing glucose homeostasis in humans. According to the latest US dietary survey, about …

[HTML][HTML] Abscisic acid: new perspectives on an ancient universal stress signaling molecule

CL Olds, EKK Glennon, S Luckhart - Microbes and Infection, 2018 - Elsevier
Few biological molecules have as far reaching and dynamic effects as abscisic acid (ABA).
In this review, we draw together the often segregated fields of plant, animal, and human …

[HTML][HTML] Insulin-independent stimulation of skeletal muscle glucose uptake by low-dose abscisic acid via AMPK activation

M Magnone, L Emionite, L Guida, T Vigliarolo… - Scientific reports, 2020 - nature.com
Abscisic acid (ABA) is a plant hormone active also in mammals where it regulates, at
nanomolar concentrations, blood glucose homeostasis. Here we investigated the …

The apocarotenoid production in microbial biofactories: An overview

R Varghese, T Buragohain, I Banerjee… - Journal of …, 2023 - Elsevier
Carotenoids are a vast group of natural pigments that come in a variety of colors ranging
from red to orange. Apocarotenoids are derived from these carotenoids, which are …

[HTML][HTML] Abscisic acid enriched fig extract promotes insulin sensitivity by decreasing systemic inflammation and activating LANCL2 in skeletal muscle

A Leber, R Hontecillas, N Tubau-Juni… - Scientific Reports, 2020 - nature.com
Abscisic acid is a phytohormone found in fruits and vegetables and is endogenously
produced in mammals. In humans and mice, lanthionine synthetase C-like 2 (LANCL2) has …

An N,N-Bis(benzimidazolylpicolinoyl)piperazine (BT-11): A Novel Lanthionine Synthetase C-Like 2-Based Therapeutic for Inflammatory Bowel Disease

A Carbo, RD Gandour, R Hontecillas… - Journal of medicinal …, 2016 - ACS Publications
Lanthionine synthetase C-like 2 (LANCL2), a novel therapeutic target for inflammatory and
autoimmune diseases and diabetes, exerts anti-inflammatory and insulin-sensitizing effects …

Phytohormone abscisic acid ameliorates neuropathic pain via regulating LANCL2 protein abundance and glial activation at the spinal cord

DW Maixner, D Christy, L Kong… - Molecular …, 2022 - journals.sagepub.com
Spinal neuroinflammation plays a critical role in the genesis of neuropathic pain.
Accumulating data suggest that abscisic acid (ABA), a phytohormone, regulates …

Abscisic acid: a phytohormone and mammalian cytokine as novel pharmacon with potential for future development into clinical applications

P Sakthivel, N Sharma, P Klahn… - Current medicinal …, 2016 - ingentaconnect.com
The isoprenoid stress-associated phytohormone abscisic acid (ABA) has recently been
recognized to possess multifaceted biological functions in mammals and to exert potent …

[HTML][HTML] Is there a role for abscisic acid, a proven anti-inflammatory agent, in the treatment of ischemic retinopathies?

P Baliño, A Gómez-Cadenas, D López-Malo… - Antioxidants, 2019 - mdpi.com
Ischemic retinopathies (IRs) are the main cause of severe visual impairment and sight loss,
and are characterized by loss of blood vessels, accompanied by hypoxia, and …