Background Pituitary carcinoma is a rare entity requiring the presence of metastasis to
confirm its malignant potential. We report a case of pituitary carcinoma and discuss the …

There have been several reports of temozolomide (TMZ) treatment of pituitary carcinomas
and atypical adenomas. O 6-methyl-guanine-DNA methyltransferase is not the sole …

Introduction Lymph node metastasis (LNM) from primary tumors of the central nervous
system (CNS) is an infrequent condition, and classically it was thought that CNS tumors …

Background: We aim to assess the role of a multidisciplinary approach in pituitary adenomas
(PitNETs) classification, evaluate criteria concordance, and compare intraoperative …

Pituitary carcinoma is extremely rare and difficult to diagnose early. Here we present a case
of highly suspected pituitary malignant adenoma with early chemotherapy and radiation. A …

Pituitary tumours, the most frequent intracranial tumour, are historically considered benign.
However, various pieces of clinical evidence and recent advances in pathological and …

Cullin 4A (CUL4A) overexpression has been reported to be involved in the carcinogenesis
and progression of many malignant tumors. However, the role of CUL4A in the progression …

Abstract Background and Importance. In the last eight years temozolomide (TMZ) has been
used as the last-line treatment modality for aggressive pituitary tumors to be applied after the …

Comparative oncology represents an important tool in cancer research and drug
development. After the sequencing of the canine genome, many similarities between canine …

Pituitary adenomas (PAs) can be unpredictable and aggressive tumors. No reliable markers
of their biological behavior have been found. Here, a proteomic analysis was applied to …