Background In this review, we examine the continually expanding and increasingly
compelling data linking radiation and various chemicals in our environment to the current …

Polycyclic aromatic hydrocarbons (PAHs) are often detected in the environment and are
regarded as endocrine disruptors. We here designated mixtures of PAHs in the environment …

Procedures for risk assessment of chemical mixtures, combined and cumulative exposures
are under development, but the scientific database needs considerable expansion. In …

DNA repair is the first barrier in the defense against genotoxic stress. In recent years,
mechanisms that recognize DNA damage and activate DNA repair functions through …

According to the published literature, we surmise that particulate matter (PM) concentration,
individually, may be less important than components in explaining health effects. PM2. 5 …

In this review we discuss the effects of exposure to complex PAH mixtures in vitro and in vivo
on mechanisms related to carcinogenesis. Of particular concern regarding exposure to …

Many chemicals in the environment can cause cancer, and polycyclic aromatic
hydrocarbons (PAHs) are among the most ubiquitous. Cancer risk assessments require …

The term polycyclic organic matter (POM) defines a broad class of compounds that generally
includes all organic structures containing three or more fused aromatic rings. These …

Our objective is to identify molecular factors which contribute to the increased risk of
smokers for oral squamous cell carcinoma (OSCC). In the present study, we investigated the …

Transcriptional regulation of DNA repair is of outmost importance for the restoration of DNA
integrity upon genotoxic stress. Here we report that the potent environmental carcinogen …