Aging is the result of the deterioration of the homeostatic systems (nervous, endocrine, and
immune systems), which preserve the organism's health. We propose that the age-related …

Pulmonary fibrosis is a chronic and fatal lung disease that significantly impacts the aging
population globally. To date, anti-fibrotic, immunosuppressive, and other adjunct therapy …

The intestinal barrier, composed of the luminal microbiota, the mucus layer, and the physical
barrier consisting of epithelial cells and immune cells, the latter residing underneath and …

Old age is associated with a greater burden of disease, including neurodegenerative
disorders such as Alzheimer's disease and Parkinson's disease, as well as other chronic …

In recent years, there has been considerable research showing that coffee consumption
seems to be beneficial to human health, as it contains a mixture of different bioactive …

Aging is characterized, amongst other features, by a complex process of cellular
senescence involving both innate and adaptive immunity, called immunosenescence and …

Obesity and ageing predispose to numerous, yet overlapping chronic diseases. For
example, metabolic abnormalities, including insulin resistance (IR) and type 2 diabetes …

The process of ageing is characteristic of multicellular organisms associated with late stages
of the lifecycle and is manifested through a plethora of phenotypes. Its underlying …

The strong interest shown in the study of the causes of aging in recent decades has
uncovered many mechanisms that could contribute to the rate of aging. These include …

Ovarian cancer is one of the most common gynecologic cancers and has the highest
mortality rate. The risk/protective factors of ovarian cancer suggest that its etiology is …