Sex differences in the intergenerational inheritance of metabolic traits

I Sandovici, DS Fernandez-Twinn, A Hufnagel… - Nature …, 2022 - nature.com
Strong evidence suggests that early-life exposures to suboptimal environmental factors,
including those in utero, influence our long-term metabolic health. This has been termed …

The mammalian preimplantation embryo: its role in the environmental programming of postnatal health and performance

MA Velazquez, A Idriss, P Chavatte-Palmer… - Animal Reproduction …, 2023 - Elsevier
During formation of the preimplantation embryo several cellular and molecular milestones
take place, making the few cells forming the early embryo vulnerable to environmental …

Role of the placenta in developmental programming: Observations from models using large animals

LP Reynolds, CR Dahlen, AK Ward, MS Crouse… - Animal Reproduction …, 2023 - Elsevier
Developmental programming, which proposes that “insults” or “stressors” during intrauterine
or postnatal development can have not only immediate but also long-term consequences for …

[HTML][HTML] Transgenerational epigenetic impacts of parental infection on offspring health and disease susceptibility

EA Kleeman, C Gubert, AJ Hannan - Trends in Genetics, 2022 - cell.com
Maternal immune activation (MIA) and infection during pregnancy are known to
reprogramme offspring phenotypes. However, the epigenetic effects of preconceptual …

Paternal dietary macronutrient balance and energy intake drive metabolic and behavioral differences among offspring

AJ Crean, AMN Senior, T Freire, TD Clark… - Nature …, 2024 - nature.com
Paternal diet can influence the phenotype of the next generation, yet, the dietary
components inducing specific responses in the offspring are not identified. Here, we use the …

Parental programming of offspring health: the intricate interplay between diet, environment, reproduction and development

V Batra, E Norman, HL Morgan, AJ Watkins - Biomolecules, 2022 - mdpi.com
As adults, our health can be influenced by a range of lifestyle and environmental factors,
increasing the risk for developing a series of non-communicable diseases such as type 2 …

Understanding the importance of the early-life period for adult health: a systematic review

JR Hildreth, MH Vickers, T Buklijas… - Journal of Developmental …, 2023 - cambridge.org
Evidence clearly indicates that the nutritional and non-nutritional environment and level of
physical activity during the early-life period from preconception through infancy has a …

Recent progress in spermatology contributing to the knowledge and conservation of rare and endangered species

P Comizzoli, WV Holt - Annual Review of Animal Biosciences, 2022 - annualreviews.org
There is a remarkable diversity in the animal kingdom regarding mechanisms underlying the
production, maturation, structure, and function of sperm cells. Spermatology studies …

The developmental origins of health and disease: adolescence as a critical lifecourse period to break the transgenerational cycle of NCDs—a narrative review

M Tohi, JL Bay, S Tu'akoi, MH Vickers - International Journal of …, 2022 - mdpi.com
Noncommunicable diseases (NCDs), including type 2 diabetes and cardiovascular disease,
represent a significant and growing global health burden. To date, a primary focus has been …

Opportunities and limitations for reproductive science in species conservation

WV Holt, P Comizzoli - Annual Review of Animal Biosciences, 2022 - annualreviews.org
Reproductive science in the context of conservation biology is often understood solely in
terms of breeding threatened species. Although technologies developed primarily for …