Sex differences in the intergenerational inheritance of metabolic traits
I Sandovici, DS Fernandez-Twinn, A Hufnagel… - Nature …, 2022 - nature.com
Strong evidence suggests that early-life exposures to suboptimal environmental factors,
including those in utero, influence our long-term metabolic health. This has been termed …
including those in utero, influence our long-term metabolic health. This has been termed …
The mammalian preimplantation embryo: its role in the environmental programming of postnatal health and performance
MA Velazquez, A Idriss, P Chavatte-Palmer… - Animal Reproduction …, 2023 - Elsevier
During formation of the preimplantation embryo several cellular and molecular milestones
take place, making the few cells forming the early embryo vulnerable to environmental …
take place, making the few cells forming the early embryo vulnerable to environmental …
Role of the placenta in developmental programming: Observations from models using large animals
Developmental programming, which proposes that “insults” or “stressors” during intrauterine
or postnatal development can have not only immediate but also long-term consequences for …
or postnatal development can have not only immediate but also long-term consequences for …
[HTML][HTML] Transgenerational epigenetic impacts of parental infection on offspring health and disease susceptibility
Maternal immune activation (MIA) and infection during pregnancy are known to
reprogramme offspring phenotypes. However, the epigenetic effects of preconceptual …
reprogramme offspring phenotypes. However, the epigenetic effects of preconceptual …
Paternal dietary macronutrient balance and energy intake drive metabolic and behavioral differences among offspring
AJ Crean, AMN Senior, T Freire, TD Clark… - Nature …, 2024 - nature.com
Paternal diet can influence the phenotype of the next generation, yet, the dietary
components inducing specific responses in the offspring are not identified. Here, we use the …
components inducing specific responses in the offspring are not identified. Here, we use the …
Parental programming of offspring health: the intricate interplay between diet, environment, reproduction and development
As adults, our health can be influenced by a range of lifestyle and environmental factors,
increasing the risk for developing a series of non-communicable diseases such as type 2 …
increasing the risk for developing a series of non-communicable diseases such as type 2 …
Understanding the importance of the early-life period for adult health: a systematic review
JR Hildreth, MH Vickers, T Buklijas… - Journal of Developmental …, 2023 - cambridge.org
Evidence clearly indicates that the nutritional and non-nutritional environment and level of
physical activity during the early-life period from preconception through infancy has a …
physical activity during the early-life period from preconception through infancy has a …
Recent progress in spermatology contributing to the knowledge and conservation of rare and endangered species
P Comizzoli, WV Holt - Annual Review of Animal Biosciences, 2022 - annualreviews.org
There is a remarkable diversity in the animal kingdom regarding mechanisms underlying the
production, maturation, structure, and function of sperm cells. Spermatology studies …
production, maturation, structure, and function of sperm cells. Spermatology studies …
The developmental origins of health and disease: adolescence as a critical lifecourse period to break the transgenerational cycle of NCDs—a narrative review
Noncommunicable diseases (NCDs), including type 2 diabetes and cardiovascular disease,
represent a significant and growing global health burden. To date, a primary focus has been …
represent a significant and growing global health burden. To date, a primary focus has been …
Opportunities and limitations for reproductive science in species conservation
WV Holt, P Comizzoli - Annual Review of Animal Biosciences, 2022 - annualreviews.org
Reproductive science in the context of conservation biology is often understood solely in
terms of breeding threatened species. Although technologies developed primarily for …
terms of breeding threatened species. Although technologies developed primarily for …