[HTML][HTML] Role of structural and non-structural proteins and therapeutic targets of SARS-CoV-2 for COVID-19

R Yadav, JK Chaudhary, N Jain, PK Chaudhary… - Cells, 2021 - mdpi.com
Coronavirus belongs to the family of Coronaviridae, comprising single-stranded, positive-
sense RNA genome (+ ssRNA) of around 26 to 32 kilobases, and has been known to cause …

[HTML][HTML] From SARS and MERS to COVID-19: a brief summary and comparison of severe acute respiratory infections caused by three highly pathogenic human …

Z Zhu, X Lian, X Su, W Wu, GA Marraro, Y Zeng - Respiratory research, 2020 - Springer
Within two decades, there have emerged three highly pathogenic and deadly human
coronaviruses, namely SARS-CoV, MERS-CoV and SARS-CoV-2. The economic burden …

The COVID-19 pandemic

M Ciotti, M Ciccozzi, A Terrinoni, WC Jiang… - Critical reviews in …, 2020 - Taylor & Francis
In December 2019, an outbreak of pneumonia of unknown origin was reported in Wuhan,
Hubei Province, China. Pneumonia cases were epidemiologically linked to the Huanan …

SARS-CoV-2 infection: The role of cytokines in COVID-19 disease

VJ Costela-Ruiz, R Illescas-Montes… - Cytokine & growth factor …, 2020 - Elsevier
COVID-19 disease, caused by infection with SARS-CoV-2, is related to a series of
physiopathological mechanisms that mobilize a wide variety of biomolecules, mainly …

[HTML][HTML] COVID-19, SARS and MERS: are they closely related?

N Petrosillo, G Viceconte, O Ergonul, G Ippolito… - Clinical microbiology …, 2020 - Elsevier
Background The 2019 novel coronavirus (SARS-CoV-2) is a new human coronavirus which
is spreading with epidemic features in China and other Asian countries; cases have also …

Clinical characteristics of 3062 COVID‐19 patients: a meta‐analysis

J Zhu, P Ji, J Pang, Z Zhong, H Li, C He… - Journal of medical …, 2020 - Wiley Online Library
We aimed to systematically review the clinical characteristics of coronavirus disease 2019
(COVID‐19). Seven databases were searched to collect studies about the clinical …

Coronavirus disease 2019: What we know?

F He, Y Deng, W Li - Journal of medical virology, 2020 - Wiley Online Library
In late December 2019, a cluster of unexplained pneumonia cases has been reported in
Wuhan, China. A few days later, the causative agent of this mysterious pneumonia was …

Effect of tocilizumab vs standard care on clinical worsening in patients hospitalized with COVID-19 pneumonia: a randomized clinical trial

C Salvarani, G Dolci, M Massari, DF Merlo… - JAMA internal …, 2021 - jamanetwork.com
Importance The coronavirus disease 2019 (COVID-19) pandemic is threatening billions of
people worldwide. Tocilizumab has shown promising results in retrospective studies in …

Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients

Y Zhou, B Fu, X Zheng, D Wang, C Zhao… - National Science …, 2020 - academic.oup.com
Pathogenic human coronavirus infections, such as severe acute respiratory syndrome CoV
(SARS-CoV) and Middle East respiratory syndrome CoV (MERS-CoV), cause high morbidity …

[PDF][PDF] Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2): an update

M Pal, G Berhanu, C Desalegn, V Kandi - Cureus, 2020 - cureus.com
Coronaviruses (CoVs) belong to the family of Coronaviridae, the order Nidovirales, and the
genus Coronavirus. They are the largest group of viruses causing respiratory and …