[HTML][HTML] Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms

H Slika, H Mansour, N Wehbe, SA Nasser… - Biomedicine & …, 2022 - Elsevier
Cancer is a leading cause of morbidity and mortality around the globe. Reactive oxygen
species (ROS) play contradicting roles in cancer incidence and progression. Antioxidants …

A review of ultrasound-assisted extraction for plant bioactive compounds: Phenolics, flavonoids, thymols, saponins and proteins

IM Yusoff, ZM Taher, Z Rahmat, LS Chua - Food research international, 2022 - Elsevier
Plant bioactive compounds are important sources for the development of food, nutraceutical,
cosmetic, and pharmaceutical products. Ultrasound-assisted extraction is one of the …

[HTML][HTML] Flavonoids against the SARS-CoV-2 induced inflammatory storm

A Liskova, M Samec, L Koklesova, SM Samuel… - Biomedicine & …, 2021 - Elsevier
The disease severity of COVID-19, especially in the elderly and patients with co-morbidities,
is characterized by hypercytokinemia, an exaggerated immune response associated with an …

The role of plant‐derived natural antioxidants in reduction of oxidative stress

B Akbari, N Baghaei‐Yazdi, M Bahmaie… - …, 2022 - Wiley Online Library
Free radicals are a group of damaging molecules produced during the normal metabolism of
cells in the human body. Exposure to ultraviolet radiation, cigarette smoking, and other …

Citrus flavonoids as promising phytochemicals targeting diabetes and related complications: A systematic review of in vitro and in vivo studies

GR Gandhi, ABS Vasconcelos, DT Wu, HB Li… - Nutrients, 2020 - mdpi.com
The consumption of plant-based food is important for health promotion, especially
concerning the prevention and management of chronic diseases. Flavonoids are the main …

Food flavonols: Nutraceuticals with complex health benefits and functionalities

D Barreca, D Trombetta, A Smeriglio… - Trends in Food Science …, 2021 - Elsevier
Background Flavonols are one of the most promising class of bioactive compounds
belonging to the broad family of the flavonoids, characterized by a unique set of features in …

The hallmarks of flavonoids in cancer

LGS Ponte, ICB Pavan, MCS Mancini, LGS da Silva… - Molecules, 2021 - mdpi.com
Flavonoids represent an important group of bioactive compounds derived from plant-based
foods and beverages with known biological activity in cells. From the modulation of …

Naringin and naringenin: Their mechanisms of action and the potential anticancer activities

J Stabrauskiene, DM Kopustinskiene, R Lazauskas… - Biomedicines, 2022 - mdpi.com
Naringin and naringenin are the main bioactive polyphenols in citrus fruits, the consumption
of which is beneficial for human health and has been practiced since ancient times …

[HTML][HTML] Flavonoids as an effective sensitizer for anti-cancer therapy: Insights into multi-faceted mechanisms and applicability towards individualized patient profiles

A Liskova, M Samec, L Koklesova, A Brockmueller… - Epma Journal, 2021 - Springer
Cost-efficacy of currently applied treatments is an issue in overall cancer management
challenging healthcare and causing tremendous economic burden to societies around the …

Nanoformulations to enhance the bioavailability and physiological functions of polyphenols

B Yang, Y Dong, F Wang, Y Zhang - Molecules, 2020 - mdpi.com
Polyphenols are micronutrients that are widely present in human daily diets. Numerous
studies have demonstrated their potential as antioxidants and anti-inflammatory agents, and …