Translating phage therapy into the clinic: Recent accomplishments but continuing challenges

A Petrovic Fabijan, J Iredell, K Danis-Wlodarczyk… - Plos …, 2023 - journals.plos.org
Phage therapy is a medical form of biological control of bacterial infections, one that uses
naturally occurring viruses, called bacteriophages or phages, as antibacterial agents …

Phage–Antibiotic therapy as a promising strategy to combat multidrug-resistant infections and to enhance antimicrobial efficiency

C Liu, Q Hong, RYK Chang, PCL Kwok, HK Chan - Antibiotics, 2022 - mdpi.com
Infections caused by multidrug-resistant (MDR) bacteria have highlighted the importance of
the development of new antimicrobial agents. While bacteriophages (phages) are widely …

Current and future direction in treatment of HPV-related cervical disease

N Khairkhah, A Bolhassani, R Najafipour - Journal of Molecular Medicine, 2022 - Springer
Human papillomavirus (HPV) is the most common sexually transmitted virus in the world.
About 70% of cervical cancers are caused by the most oncogenic HPV genotypes of 16 and …

Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant Acinetobacter baumannii

Y Tan, J Su, M Fu, H Zhang, H Zeng - Bioengineering, 2022 - mdpi.com
Acinetobacter baumannii is an important opportunistic pathogen common in clinical
infections. Phage therapy become a hot research field worldwide again after the post …

Bacteriophage-based techniques for elucidating the function of zebrafish gut microbiota

PP Jia, YF Yang, M Junaid, HJ Jia, WG Li… - Applied Microbiology and …, 2023 - Springer
Bacteriophages (or phages) are unique viruses that can specifically infect bacteria. Since
their discovery by Twort and d'Herelle, phages with bacterial specificity have played …

Trojan Horse virus delivering CRISPR-AsCas12f1 controls plant bacterial wilt caused by Ralstonia solanacearum

S Peng, Y Xu, H Qu, F Nong, F Shu, G Yuan, L Ruan… - Mbio, 2024 - journals.asm.org
Plant bacterial wilt caused by Ralstonia solanacearum results in huge losses. Accordingly,
developing an effective control method for this disease is urgently required. Filamentous …

Genetically engineered microorganisms and their impact on human health

M Mahdizade Ari, L Dadgar, Z Elahi… - … Journal of Clinical …, 2024 - Wiley Online Library
The emergence of antibiotic‐resistant strains, the decreased effectiveness of conventional
therapies, and the side effects have led researchers to seek a safer, more cost‐effective …

The biotechnological application of bacteriophages: what to do and where to go in the middle of the post-antibiotic era

SJ Jo, J Kwon, SG Kim, SJ Lee - Microorganisms, 2023 - mdpi.com
Amid the escalating challenges of antibiotic resistance, bacterial infections have emerged as
a global threat. Bacteriophages (phages), viral entities capable of selectively infecting …

The Medicinal Phage—Regulatory Roadmap for Phage Therapy under EU Pharmaceutical Legislation

T Faltus - Viruses, 2024 - mdpi.com
Bacteriophage therapy is a promising approach to treating bacterial infections. Research
and development of bacteriophage therapy is intensifying due to the increase in antibiotic …

Bacteriophage as a Potential Biotherapeutics to Combat Present-Day Crisis of Multi-Drug Resistant Pathogens

A Pattnaik, S Pati, SK Samal - Heliyon, 2024 - cell.com
The rise of Multi-Drug Resistant (MDR) bacterial pathogens to most, if not all, currently
available antibacterial agents has become a global threat. As a consequence of the …