[HTML][HTML] Idiosyncratic DILI and RUCAM under one hat: The global view

R Teschke, G Danan - Livers, 2023 - mdpi.com
Drugs are prescribed worldwide to treat diseases but with the risk of idiosyncratic drug-
induced liver injury (iDILI). The most important difficulty is how best to establish causality …

[HTML][HTML] Pharmacokinetic Simulation Study: Exploring the Impact of Clinical Parameters on Lamotrigine for Different Patient Populations with Implications for Liver …

B Costa, I Silva, JC Oliveira, H Reguengo… - Scientia Pharmaceutica, 2024 - mdpi.com
Lamotrigine, widely used for managing epilepsy and bipolar disorder, carries potential side
effects, including severe anticonvulsant hypersensitivity syndrome (AHS) or drug rash with …

药物诱导的自身免疫样肝炎的研究进展.

李勤荣, 尧颖, 徐智媛 - Journal of Clinical Hepatology …, 2024 - search.ebscohost.com
药物诱导的自身免疫样肝炎(DI-ALH) 是药物性肝损伤的一种特殊临床表型,
与自身免疫性肝炎有相似的临床特征和实验室检查, 多数时候通过肝组织活检也无法直接区分 …

[HTML][HTML] Idiosyncratic DILI: Immunology in Cases with Evidence Based on RUCAM

R Teschke - Journal of Modern Medicinal Chemistry, 2023 - synergypublishers.com
Idiosyncratic drug induced liver injury (iDILI) is a multifaceted and fairly well described liver
disease, but there is yet some uncertainty on the role of immune systems triggering the liver …