Hypotheses are scaffoldings erected in front of a building and then dismantled when the
building is finished. They are indispensable for the workman; but you mustn't mistake the …

Background Hippocampal volume loss is a hallmark of clinical depression. Chronic stress
produces volume loss in the hippocampus in humans and atrophy of CA3 pyramidal cells …

Adult neurogenesis, the process of generating new neurons from neural stem cells, plays
significant roles in synaptic plasticity, memory, and mood regulation. In the mammalian …

Exposure to prolonged stress results in structural and functional alterations in the
hippocampus including reduced long‐term potentiation (LTP), neurogenesis, spatial …

Severe depression compromises structural and functional integrity of the brain and results in
impaired learning and memory, maladaptive synaptic plasticity as well as degenerative …

Stress is known to inhibit neuronal growth in the hippocampus. In addition to reducing the
size and complexity of the dendritic tree, stress and elevated glucocorticoid levels are known …

During development, the brain goes through fundamental processes, including organization
of neural networks and plasticity. Environmental interventions may change initial brain …

The heteroreceptor complexes present a novel biological principle for signal integration.
These complexes and their allosteric receptor–receptor interactions are bidirectional and …

With the increasing evidences of cadmium-induced cognitive deficits associated with brain
cholinergic dysfunctions, the present study aimed to decipher molecular mechanisms …

Adult hippocampal neurogenesis is a remarkable form of brain structural plasticity by which
new functional neurons are generated from adult neural stem cells/precursors. Although the …