Polyphenols are naturally occurring compounds in plants and they are the most abundant
antioxidants in the human diet. Due to their considerable structural diversity, this largely …

Ellagic acid is a common metabolite present in many medicinal plants and vegetables. It is
present either in free form or as part of more complex molecules (ellagitannins), which can …

Innate immune response induces positive inflammatory transducers and regulators in order
to attack pathogens, while simultaneously negative signaling regulators are transcribed to …

Oxidative stress (OS) is considered as one of the etiologic factors involved in several signals
and symptoms of inflammatory bowel diseases (IBD) that include diarrhea, toxic megacolon …

Inflammation is commonly characterized as a defensive and protective reaction of the body
to various exogenous or endogenous stimuli, which aims to maintain the body health …

Ellagic acid (EA) is a dietary polyphenol present in various fruits, vegetables, herbs, and
nuts. It exists either independently or as part of complex structures, such as ellagitannins …

Ellagitannins (ETs) are a large group of bioactive compounds found in plant-source foods,
such as pomegranates, berries, and nuts. The consumption of ETs has often been …

Background: Pomegranate (Punica granatum L.) fruits are widely consumed and used as
preventive and therapeutic agents since ancient times. Pomegranate is a rich source of a …

TLR4/NF-κB is a key inflammatory signaling transduction pathway, closely involved in cell
differentiation, proliferation, apoptosis, and pro-inflammatory response. Toll like receptor 4 …

Worldwide, colorectal cancer (CRC) remains a major cancer type and leading cause of
death. Unfortunately, current medical treatments are not sufficient due to lack of effective …