Therapeutic Potential of Quercetin-Loaded Nanoemulsion against Experimental Visceral Leishmaniasis: In Vitro/Ex Vivo Studies and Mechanistic Insights

SS Das, AK Dubey, PRP Verma, SK Singh… - Molecular …, 2022 - ACS Publications
Visceral leishmaniasis (VL) is one of the most fatal and neglected tropical diseases caused
by Leishmania donovani (L. donovani). The applications of currently available …

Promising effects of herbal compounds against strongyloidiasis: a systematic review

A Soleimani, N Keivani, S Lotfipour… - Journal of Parasitic …, 2022 - Springer
Strongyloidiasis could be a significant global health issue undervalued in several countries,
which is caused by Strongyloides spp. Challenges stemming from the use of anthelmintic …

Identification of potential anti-leishmanial compounds from natural sources against citrate synthase enzyme using structure-based drug designing

P Ranjan, VK Dubey - Journal of Molecular Structure, 2024 - Elsevier
Leishmaniasis, an infectious parasitic disease, has been targeted for elimination by World
Health Organization. This study, natural compounds were selected from the ZINC 15 …

Exploring the Immunotherapeutic Potential of Oleocanthal against Murine Cutaneous Leishmaniasis

K Karampetsou, OS Koutsoni, F Badounas… - Planta …, 2022 - thieme-connect.com
Leishmaniasis is a major tropical disease with increasing global incidence. Due to limited
therapeutic options with severe drawbacks, the discovery of alternative treatments based on …

Antiproliferative activity on Trypanosoma cruzi (Y strain) of the triterpene 3β,6β,16β-trihidroxilup-20 (29)-ene isolated from Combretum leprosum

JIF de Araújo, NL Aires… - Journal of …, 2022 - Taylor & Francis
Chagas disease infects approximately seven million people worldwide. Benznidazole is
effective only in the acute phase of the disease, with an average cure rate of 80% between …

Cutaneous Leishmaniasis: Physiopathology, Molecular Diagnostic, and Therapeutic Approaches

A Balahbib, A Hmamouch, A El Allam… - Progress In Microbes …, 2023 - hh-publisher.com
This in-depth study explores various aspects of cutaneous leishmaniasis, shedding light on
the physiopathology of the infection, advances in molecular diagnostic techniques, and …

Leishmanicidal activity of Morita-Baylis–Hillman adducts

ACS Vieira, M da Silva Santos, AB Leite… - Parasitology …, 2022 - Springer
Leishmaniasis is a neglected disease that affects millions of people, mostly in developing
countries. Although this disease has a high impact on public health, there are few drug …

Direct In Vitro Comparison of the Anti-Leishmanial Activity of Different Olive Oil Total Polyphenolic Fractions and Assessment of Their Combined Effects with …

G Gogou, OS Koutsoni, P Stathopoulos, LA Skaltsounis… - Molecules, 2022 - mdpi.com
The bioactive compounds present in the edible products of the olive tree have been
extensively studied and their favorable effects on various disease risk factors have been …

[HTML][HTML] In vitro Evaluation of the Potent Antileishmanial Activity of Ferula tabasensis Alone or in Combination with Shark Cartilage Extract Against the Standard Iranian …

S Saraei, N Soozangar, M Miran… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Background The available drugs for the treatment of leishmaniasis are highly toxic and
extremely expensive, with low efficiency; therefore, the development of effective therapeutic …

Structure modifications of 2-phenylquinoline by Aspergillus genera produce novel derivatives with potent leishmanicidal and anti-inflammatory properties

KL Mischiatti, IC Pimentel, L Donatti… - Journal of Molecular …, 2022 - Elsevier
Quinolines are heterocyclic molecules with a wide range of pharmacological purposes. The
quinolinic system has been used for the synthesis of derivatives, producing molecules with …