Recent approaches for angiogenesis in search of successful tissue engineering and regeneration

LVK Reddy, D Murugan, M Mullick… - Current Stem Cell …, 2020 - ingentaconnect.com
Angiogenesis plays a central role in human physiology from reproduction and fetal
development to wound healing and tissue repair/regeneration. Clinically relevant therapies …

Impact of diabetes mellitus on human mesenchymal stromal cell biology and functionality: implications for autologous transplantation

M Mahmoud, N Abu-Shahba, O Azmy… - Stem cell reviews and …, 2019 - Springer
Multipotent mesenchymal stem/stromal cells (MSCs) have regenerative and
immunomodulatory properties to restore and repair injured tissues, making them attractive …

[HTML][HTML] Multi-parameter analysis of biobanked human bone marrow stromal cells shows little influence for donor age and mild comorbidities on phenotypic and …

A Andrzejewska, R Catar, J Schoon, TH Qazi… - Frontiers in …, 2019 - frontiersin.org
Heterogeneous populations of human bone marrow-derived stromal cells (BMSC) are
among the most frequently tested cellular therapeutics for treating degenerative and immune …

A novel platelet lysate hydrogel for endothelial cell and mesenchymal stem cell-directed neovascularization

ST Robinson, AM Douglas, T Chadid, K Kuo… - Acta biomaterialia, 2016 - Elsevier
Mesenchymal stem cells (MSC) hold promise in promoting vascular regeneration of
ischemic tissue in conditions like critical limb ischemia of the leg. However, this approach …

Impact of type 2 diabetes mellitus on the immunoregulatory characteristics of adipose tissue-derived mesenchymal stem cells

N Abu-Shahba, M Mahmoud, AM El-Erian… - The international journal …, 2021 - Elsevier
Background Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder associated
with several complications. Adipose tissue-derived mesenchymal stem cells (AT-MSCs) …

[HTML][HTML] Modulation of mesenchymal stem cells for enhanced therapeutic utility in ischemic vascular diseases

SL Elshaer, SH Bahram, P Rajashekar… - International Journal of …, 2021 - mdpi.com
Mesenchymal stem cells are multipotent stem cells isolated from various tissue sources,
including but not limited to bone marrow, adipose, umbilical cord, and Wharton Jelly …

[HTML][HTML] Diabetes-induced glucolipotoxicity impairs wound healing ability of adipose-derived stem cells-through the miR-1248/CITED2/HIF-1α pathway

S Xiao, D Zhang, Z Liu, W Jin, G Huang, Z Wei… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Despite being an attractive cell type for mesenchymal stem cell (MSC) transplantation
therapy for wound healing, human adipose-derived stem cells (hADSCs) from diabetes …

[HTML][HTML] In vivo efficacy of endothelial growth medium stimulated mesenchymal stem cells derived from patients with critical limb ischemia

R Al-Rifai, P Nguyen, N Bouland, C Terryn… - Journal of Translational …, 2019 - Springer
Background Cell therapy has been proposed for patients with critical limb ischemia (CLI).
Autologous bone marrow derived cells (BMCs) have been mostly used, mesenchymal stem …

Mesenchymal stromal cell characteristics and regenerative potential in cardiovascular disease: Implications for cellular therapy

FCC van Rhijn-Brouwer, H Gremmels… - Cell …, 2018 - journals.sagepub.com
Administration of mesenchymal stromal cells (MSCs) is a promising strategy to treat
cardiovascular disease (CVD). As progenitor cells may be negatively affected by both age …

MicroRNA‐139‐5p mediates BMSCs impairment in diabetes by targeting HOXA9/c‐Fos

F Liang, Y Luo, Z Guo, Q Qian, XB Meng… - The FASEB …, 2023 - Wiley Online Library
The properties and functions of BMSCs were altered by the diabetic microenvironment, and
its mechanism was not very clear. In recent years, the regulation of the function of BMSCs by …