Upregulation of sialyltransferases—the enzymes responsible for the addition of sialic acid to
growing glycoconjugate chains—and the resultant hypersialylation of up to 40–60% of …

Glycomics aims to identify the structure and function of the glycome, the complete set of
oligosaccharides (glycans), produced in a given cell or organism, as well as to identify …

As an emerging new class, metal nanoparticles and especially silver nanoparticles hold
great potential in the field of cancer biology. Due to cancer-specific targeting, the …

In recent years, the second-highest mortality rate of any cancer worldwide has been breast
cancer (BC), which is one of the three most common and deadly cancers among women …

BACKGROUND. Although aberrant glycosylation is recognized as a hallmark of cancer,
glycosylation in clinical breast cancer (BC) metastasis has not yet been studied. While …

Glycosylation is an important posttranslational modifier of proteins and lipid conjugates
critical for the stability and function of these macromolecules. Particularly important are N …

This comprehensive review paper describes recent advances made in the field of
electrochemical nanobiosensors for the detection of breast cancer (BC) biomarkers such as …

This review is the tenth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …

Immunohistochemistry (IHC) is still widely used as a morphology-based assay for in situ
analysis of target proteins as specific tumor antigens. However, as a very heterogeneous …

Glycosylation is one of the most significant and abundant post-translational modifications in
cells. Glycomic and glycoproteomic analyses involve the characterization of …