abstract Galleria mellonella (greater wax moth or honeycomb moth) has been introduced as
an alternative model to study microbial infections. G. mellonella larvae can be easily and …

The first research on the insect Galleria mellonella was published 85 years ago, and the
larva is now widely used as a model to study infections caused by bacterial and fungal …

Bacteriophage therapy has been suggested as an alternative or complementary strategy for
the treatment of multidrug resistant (MDR) bacterial infections. Here, we report the …

Background Infectivity trials and toxicity testing in rodents are important prerequisites to the
use of compounds in man. However, trials in rats and mice are expensive and there are …

Inhaled antibiotics, such as tobramycin, for the treatment of Pseudomonas aeruginosa
pulmonary infections are associated with the increase in life expectancy seen in cystic …

Background and objectives Antimicrobial resistance is a growing global concern and has
spurred increasing efforts to find alternative therapeutics. Bacteriophage therapy has seen …

Many bacteria use the second messenger cyclic diguanylate (c-di-GMP) to control motility,
biofilm production and virulence. Here, we identify a thermosensory diguanylate cyclase …

Background In comparison to synthetically derived surfactants, biosurfactants produced from
microbial culture are generally regarded by industry as being more sustainable and possess …

Antimicrobial resistance in Gram-negative bacteria is one of the greatest threats to global
health. New antibacterial strategies are urgently needed, and the development of antibiotic …

Microbiomes are rife for biotechnological exploitation, particularly the rumen microbiome,
due to their complexicity and diversity. In this study, antimicrobial peptides (AMPs) from the …