Galleria mellonella infection models for the study of bacterial diseases and for antimicrobial drug testing
CJY Tsai, JMS Loh, T Proft - Virulence, 2016 - Taylor & Francis
abstract Galleria mellonella (greater wax moth or honeycomb moth) has been introduced as
an alternative model to study microbial infections. G. mellonella larvae can be easily and …
an alternative model to study microbial infections. G. mellonella larvae can be easily and …
The Virtuous Galleria mellonella Model for Scientific Experimentation
I Serrano, C Verdial, L Tavares, M Oliveira - Antibiotics, 2023 - mdpi.com
The first research on the insect Galleria mellonella was published 85 years ago, and the
larva is now widely used as a model to study infections caused by bacterial and fungal …
larva is now widely used as a model to study infections caused by bacterial and fungal …
Personalized aerosolised bacteriophage treatment of a chronic lung infection due to multidrug-resistant Pseudomonas aeruginosa
T Köhler, A Luscher, L Falconnet, G Resch… - Nature …, 2023 - nature.com
Bacteriophage therapy has been suggested as an alternative or complementary strategy for
the treatment of multidrug resistant (MDR) bacterial infections. Here, we report the …
the treatment of multidrug resistant (MDR) bacterial infections. Here, we report the …
Galleria mellonella (greater wax moth) larvae as a model for antibiotic susceptibility testing and acute toxicity trials
K Ignasiak, A Maxwell - BMC research notes, 2017 - Springer
Background Infectivity trials and toxicity testing in rodents are important prerequisites to the
use of compounds in man. However, trials in rats and mice are expensive and there are …
use of compounds in man. However, trials in rats and mice are expensive and there are …
Antimicrobial efficacy of tobramycin polymeric nanoparticles for Pseudomonas aeruginosa infections in cystic fibrosis: formulation, characterisation and …
J Deacon, SM Abdelghany, DJ Quinn, D Schmid… - Journal of Controlled …, 2015 - Elsevier
Inhaled antibiotics, such as tobramycin, for the treatment of Pseudomonas aeruginosa
pulmonary infections are associated with the increase in life expectancy seen in cystic …
pulmonary infections are associated with the increase in life expectancy seen in cystic …
Phage steering of antibiotic-resistance evolution in the bacterial pathogen, Pseudomonas aeruginosa
Background and objectives Antimicrobial resistance is a growing global concern and has
spurred increasing efforts to find alternative therapeutics. Bacteriophage therapy has seen …
spurred increasing efforts to find alternative therapeutics. Bacteriophage therapy has seen …
Bacterial cyclic diguanylate signaling networks sense temperature
H Almblad, TE Randall, F Liu, K Leblanc… - Nature …, 2021 - nature.com
Many bacteria use the second messenger cyclic diguanylate (c-di-GMP) to control motility,
biofilm production and virulence. Here, we identify a thermosensory diguanylate cyclase …
biofilm production and virulence. Here, we identify a thermosensory diguanylate cyclase …
Biosynthesis of rhamnolipid by a Marinobacter species expands the paradigm of biosurfactant synthesis to a new genus of the marine microflora
Background In comparison to synthetically derived surfactants, biosurfactants produced from
microbial culture are generally regarded by industry as being more sustainable and possess …
microbial culture are generally regarded by industry as being more sustainable and possess …
Breaking antimicrobial resistance by disrupting extracytoplasmic protein folding
RCD Furniss, N Kaderabkova, D Barker, P Bernal… - Elife, 2022 - elifesciences.org
Antimicrobial resistance in Gram-negative bacteria is one of the greatest threats to global
health. New antibacterial strategies are urgently needed, and the development of antibiotic …
health. New antibacterial strategies are urgently needed, and the development of antibiotic …
Microbiome-derived antimicrobial peptides offer therapeutic solutions for the treatment of Pseudomonas aeruginosa infections
AJ Mulkern, LB Oyama, AR Cookson… - npj Biofilms and …, 2022 - nature.com
Microbiomes are rife for biotechnological exploitation, particularly the rumen microbiome,
due to their complexicity and diversity. In this study, antimicrobial peptides (AMPs) from the …
due to their complexicity and diversity. In this study, antimicrobial peptides (AMPs) from the …