Lithium and its effects: does dose matter?
M Manchia, P Paribello, M Pinna, L Steardo Jr… - International journal of …, 2024 - Springer
Background Decades of clinical research have demonstrated the efficacy of lithium in
treating acute episodes (both manic and depressive), as well as in preventing recurrences of …
treating acute episodes (both manic and depressive), as well as in preventing recurrences of …
[HTML][HTML] Lithium Ions as Modulators of Complex Biological Processes: The Conundrum of Multiple Targets, Responsiveness and Non-Responsiveness, and the …
DA Hart - Biomolecules, 2024 - mdpi.com
Lithium is one of the lightest elements on Earth and it has been in the environment since the
formation of the galaxy. While a common element, it has not been found to be an essential …
formation of the galaxy. While a common element, it has not been found to be an essential …
Mature neurons from iPSCs unveil neurodegeneration-related pathways in mucopolysaccharidosis type II: GSK-3β inhibition for therapeutic potential
TY Chen, SP Lin, DF Huang, HS Huang, FC Tsai… - Cell Death & …, 2024 - nature.com
Mucopolysaccharidosis (MPS) type II is caused by a deficiency of iduronate-2-sulfatase and
is characterized by the accumulation of glycosaminoglycans (GAGs). Without effective …
is characterized by the accumulation of glycosaminoglycans (GAGs). Without effective …
Connecting GSK-3β Inhibitory Activity with IKK-β or ROCK-1 Inhibition to Target Tau Aggregation and Neuroinflammation in Alzheimer's Disease—Discovery, In Vitro …
I Góral, T Wichur, E Sługocka, J Godyń, N Szałaj… - Molecules, 2024 - mdpi.com
GSK-3β, IKK-β, and ROCK-1 kinases are implicated in the pathomechanism of Alzheimer's
disease due to their involvement in the misfolding and accumulation of amyloid β (Aβ) and …
disease due to their involvement in the misfolding and accumulation of amyloid β (Aβ) and …
[HTML][HTML] MiR-29a efficiently suppresses the generation of reactive oxygen species and α-synuclein in a cellular model of Parkinson's disease by potentially targeting …
Abstract MicroRNA-29a (miR-29a) has been suggested to serve a potential protective
function against Parkinson's disease (PD); however, the exact molecular mechanisms …
function against Parkinson's disease (PD); however, the exact molecular mechanisms …
Alzheimer's disease and low-dose radiation therapy: A new hope
NE Dunlap, RP Friedland, L Cai - Radiation medicine and protection, 2024 - mednexus.org
The concept of low-dose radiation (LDR)-induced hormetic responses was initially observed
approximately 70 years ago and systematically reviewed along with the discovery of LDR …
approximately 70 years ago and systematically reviewed along with the discovery of LDR …