A review of classification, biosynthesis, biological activities and potential applications of flavonoids

S Chen, X Wang, Y Cheng, H Gao, X Chen - Molecules, 2023 - mdpi.com
Flavonoids represent the main class of plant secondary metabolites and occur in the tissues
and organs of various plant species. In plants, flavonoids are involved in many biological …

Minor tropical fruits as a potential source of bioactive and functional foods

T Sarkar, M Salauddin, A Roy, N Sharma… - Critical Reviews in …, 2023 - Taylor & Francis
Tropical fruits are defined as fruits that are grown in hot and humid regions within the Tropic
of Cancer and Tropic of Capricorn, covering most of the tropical and subtropical areas of …

Astaxanthin Protects Ochratoxin A‐Induced Oxidative Stress and Apoptosis in the Heart via the Nrf2 Pathway

G Cui, L Li, W Xu, M Wang, D Jiao… - Oxidative medicine …, 2020 - Wiley Online Library
This study assessed the protective mechanism of astaxanthin (ASX) against ochratoxin A‐
(OTA‐) induced cardiac injury in mice. Four groups of mice were established: control group …

Natural products targeting PI3K/AKT in myocardial ischemic reperfusion injury: A scoping review

SA Syed Abd Halim, N Abd Rashid, CK Woon… - Pharmaceuticals, 2023 - mdpi.com
This scoping review aimed to summarize the effects of natural products targeting
phosphoinositide-3-kinases/serine/threonine kinase (PI3K/AKT) in myocardial ischemia …

Potentilla anserina polysaccharide alleviates cadmium-induced oxidative stress and apoptosis of H9c2 cells by regulating the MG53-mediated RISK pathway

Z Lixia, J Cheng, LIU Di, G Hongxia… - Chinese Journal of …, 2023 - Elsevier
Oxidative stress plays a crucial role in cadmium (Cd)-induced myocardial injury. Mitsugumin
53 (MG53) and its mediated reperfusion injury salvage kinase (RISK) pathway have been …

Discussion on the structural modification and anti-tumor activity of flavonoids

ZG Zhou, DD Li, Y Chen, X Chen… - Current Topics in …, 2022 - ingentaconnect.com
Flavonoids are secondary metabolites of plants. In general# 140; most flavonoids are
combined with glucosides and have extremely complex molecular structures. In nature …

Hydroxysafflor yellow A inhibits hypoxia/reoxygenation-induced cardiomyocyte injury via regulating the AMPK/NLRP3 inflammasome pathway

J Ye, M Wang, R Wang, H Liu, Y Qi, J Fu… - International …, 2020 - Elsevier
Hydroxysafflor yellow A (HSYA) is an effective therapeutic agent that alleviates myocardial
ischaemia/reperfusion injury (MIRI), but the exact mechanisms remain elusive. The aim of …

An overview of the nutritional value, health properties, and future challenges of Chinese bayberry

S Zhang, Z Yu, L Sun, H Ren, X Zheng, S Liang, X Qi - PeerJ, 2022 - peerj.com
Chinese bayberry (CB) is among the most popular and valuable fruits in China owing to its
attractive color and unique sweet/sour taste. Recent studies have highlighted the nutritional …

The signaling interplay of GSK-3β in myocardial disorders

AK Sharma, PV Thanikachalam, S Bhatia - Drug Discovery Today, 2020 - Elsevier
Highlights•GSK-3β regulates various upstream and downstream effectors in the
heart.•Activation of GSK-3β cascade negatively regulate the cardiac physiology.• …

Sulforaphane Attenuates Isoproterenol‐Induced Myocardial Injury in Mice

L Song, M Srilakshmi, Y Wu… - BioMed Research …, 2020 - Wiley Online Library
The development of isoproterenol‐(ISO‐) induced oxidative stress in the myocardium results
in myocardial necrosis. Sulforaphane (SFN‐0.4% of sulforaphane from standardized …