Plant biosynthetic gene clusters in the context of metabolic evolution
SJ Smit, BR Lichman - Natural Product Reports, 2022 - pubs.rsc.org
Covering: up to 2022 Plants produce a wide range of structurally and biosynthetically
diverse natural products to interact with their environment. These specialised metabolites …
diverse natural products to interact with their environment. These specialised metabolites …
Subcellular compartmentalization in the biosynthesis and engineering of plant natural produces
L Yao, X Wu, X Jiang, M Shan, Z Zhang, Y Li… - Biotechnology …, 2023 - Elsevier
Plant natural products (PNPs) are specialized metabolites with diverse bioactivities. They
are extensively used in the pharmaceutical, cosmeceutical and food industries. PNPs are …
are extensively used in the pharmaceutical, cosmeceutical and food industries. PNPs are …
NextDenovo: an efficient error correction and accurate assembly tool for noisy long reads
Long-read sequencing data, particularly those derived from the Oxford Nanopore
sequencing platform, tend to exhibit high error rates. Here, we present NextDenovo, an …
sequencing platform, tend to exhibit high error rates. Here, we present NextDenovo, an …
Revealing evolution of tropane alkaloid biosynthesis by analyzing two genomes in the Solanaceae family
F Zhang, F Qiu, J Zeng, Z Xu, Y Tang, T Zhao… - Nature …, 2023 - nature.com
Tropane alkaloids (TAs) are widely distributed in the Solanaceae, while some important
medicinal tropane alkaloids (mTAs), such as hyoscyamine and scopolamine, are restricted …
medicinal tropane alkaloids (mTAs), such as hyoscyamine and scopolamine, are restricted …
Emerging mechanistic insights into the regulation of specialized metabolism in plants
Plants biosynthesize a broad range of natural products through specialized and species-
specific metabolic pathways that are fuelled by core metabolism, together forming a …
specific metabolic pathways that are fuelled by core metabolism, together forming a …
Subgenome-aware analyses suggest a reticulate allopolyploidization origin in three Papaver genomes
RG Zhang, C Lu, GY Li, J Lv, L Wang, ZX Wang… - Nature …, 2023 - nature.com
Hybridization and polyploidization are important driving forces in angiosperm evolution,
resulting in novel phenotypes capable of prompting ecological diversification and invasion …
resulting in novel phenotypes capable of prompting ecological diversification and invasion …
Characterization of the horse chestnut genome reveals the evolution of aescin and aesculin biosynthesis
W Sun, Q Yin, H Wan, R Gao, C Xiong, C Xie… - Nature …, 2023 - nature.com
Horse chestnut (Aesculus chinensis) is an important medicinal tree that contains various
bioactive compounds, such as aescin, barrigenol-type triterpenoid saponins (BAT), and …
bioactive compounds, such as aescin, barrigenol-type triterpenoid saponins (BAT), and …
Functional divergence of CYP76AKs shapes the chemodiversity of abietane-type diterpenoids in genus Salvia
Abstract The genus Salvia L.(Lamiaceae) comprises myriad distinct medicinal herbs, with
terpenoids as one of their major active chemical groups. Abietane-type diterpenoids (ATDs) …
terpenoids as one of their major active chemical groups. Abietane-type diterpenoids (ATDs) …
Uncovering a miltiradiene biosynthetic gene cluster in the Lamiaceae reveals a dynamic evolutionary trajectory
The spatial organization of genes within plant genomes can drive evolution of specialized
metabolic pathways. Terpenoids are important specialized metabolites in plants with diverse …
metabolic pathways. Terpenoids are important specialized metabolites in plants with diverse …
TCMPG: an integrative database for traditional Chinese medicine plant genomes
Because of their great therapeutic and economic value, medicinal plants have attracted
increasing scientific attention. With the rapid development of high-throughput sequencing …
increasing scientific attention. With the rapid development of high-throughput sequencing …