LPIN1 rs13412852 polymorphism in pediatric nonalcoholic fatty liver disease

L Valenti, BM Motta, A Alisi, R Sartorelli… - Journal of pediatric …, 2012 - journals.lww.com
Objectives: The aim of the present study was to evaluate whether the lipin1 rs13412852 C>
T polymorphism is associated with nonalcoholic steatohepatitis and fibrosis in pediatric …

Metabolic disorders induced by PNPLA3 and TM6SF2 gene variants affect chronic kidney disease in patients infected with non-genotype 3 hepatitis C virus

J Liu, W Qi, S Wang, Y Zhang, X Wang, D Sun… - Lipids in Health and …, 2023 - Springer
Background Patients with chronic hepatitis C virus (HCV) infections differ in their risk for
metabolic disorders and chronic kidney disease (CKD). The aim of this study was to …

Genetic factors that affect spontaneous clearance of hepatitis C or B virus, response to treatment, and disease progression

TR O'Brien, HI Yang, S Groover, WJ Jeng - Gastroenterology, 2019 - Elsevier
Hepatitis C virus (HCV) and hepatitis B virus (HBV) infections can lead to cirrhosis, end-
stage liver disease, and hepatocellular carcinoma. Over the past decade, studies of …

[HTML][HTML] Genetic modifiers of non-alcoholic fatty liver disease progression

QM Anstee, AK Daly, CP Day - … et Biophysica Acta (BBA)-Molecular Basis …, 2011 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is now recognised as the most common cause of
liver dysfunction worldwide. However, whilst the majority of individuals who exhibit features …

The i148m Pnpla3 polymorphism influences serum adiponectin in patients with fatty liver and healthy controls

L Valenti, R Rametta, M Ruscica, P Dongiovanni… - BMC …, 2012 - Springer
Background Reduced adiponectin is implicated in the pathogenesis of nonalcoholic fatty
liver disease (NAFLD) and steatohepatitis (NASH), and the I148M Patatin-like …

Natural history of hepatic and extrahepatic hepatitis C virus diseases and impact of interferon-free HCV therapy

F Negro - Cold Spring Harbor perspectives in …, 2020 - perspectivesinmedicine.cshlp.org
The hepatitis C virus (HCV) infects 71.1 million persons and causes 400,000 deaths
annually worldwide. HCV mostly infects the liver, causing acute and chronic …

Genetics of alcoholic liver disease

QM Anstee, AK Daly, CP Day - Seminars in liver disease, 2015 - thieme-connect.com
Excess alcohol consumption with consequent alcoholic liver disease (ALD) is a common
cause of liver dysfunction and liver-related mortality worldwide. However, although the …

Correlation between PNPLA3 rs738409 polymorphism and hepatocellular carcinoma: a meta-analysis of 10,330 subjects

Z Huang, X Guo, G Zhang, L Liang… - … International journal of …, 2019 - journals.sagepub.com
Purpose: The correlation between patatin-like phospholipase domain-containing protein 3
(PNPLA3) rs738409 polymorphism and hepatocellular carcinoma was investigated by …

PNPLA3 I148M polymorphism, clinical presentation, and survival in patients with hepatocellular carcinoma

L Valenti, BM Motta, G Soardo, M Iavarone, B Donati… - PLoS …, 2013 - journals.plos.org
Background & Aims Aim of this study was to evaluate whether the PNPLA3 I148M
polymorphism, previously associated with hepatocellular carcinoma (HCC) risk, influences …

The effect of the TM6SF2 E167K variant on liver steatosis and fibrosis in patients with chronic hepatitis C: a meta-analysis

Z Liu, S Que, L Zhou, S Zheng, S Romeo… - Scientific reports, 2017 - nature.com
The impact of Transmembrane 6 superfamily member 2 (TM6SF2) E167K variant, which
causes hepatocellular fat retention by altering lipoprotein secretion, on liver damage and …