Impact of PNPLA3 I148M on alpha-1 antitrypsin deficiency-dependent liver disease progression

I Volkert, M Fromme, C Schneider, L Candels… - Hepatology, 2024 - journals.lww.com
Impact of PNPLA3 I148M on alpha-1 antitrypsin deficiency-dep... : Hepatology Impact of
PNPLA3 I148M on alpha-1 antitrypsin deficiency-dependent liver disease progression …

Abdominal fat interacts with PNPLA 3 I148M, but not with the APOC 3 variant in the pathogenesis of liver steatosis in chronic hepatitis C

R Zampino, N Coppola, G Cirillo… - Journal of Viral …, 2013 - Wiley Online Library
The patatin‐like phospholipase domain‐containing 3 gene (PNPLA 3) and the
apolipoprotein C3 gene (APOC 3) have been studied in relation to liver steatosis and liver …

PNPLA3 148M Carriers with Inflammatory Bowel Diseases Have Higher Susceptibility to Hepatic Steatosis and Higher Liver Enzymes

RM Mancina, R Spagnuolo, M Milano… - Inflammatory Bowel …, 2016 - academic.oup.com
Background Inflammatory bowel diseases (IBD) are characterized by chronic relapsing
inflammation of the gastrointestinal tract and encompass Crohn's disease and ulcerative …

[HTML][HTML] Patatin-like phospholipase domain containing-3 gene I148M polymorphism, steatosis, and liver damage in hereditary hemochromatosis

L Valenti, P Maggioni, A Piperno… - World Journal of …, 2012 - ncbi.nlm.nih.gov
AIM: To investigate whether the patatin-like phospholipase domain containing-3 gene
(PNPLA3) I148M polymorphism is associated with steatosis, fibrosis stage, and cirrhosis in …

Steatosis is an independent predictor of relapse following rapid virologic response in patients with HCV genotype 3

SR Shah, K Patel, P Marcellin, GR Foster… - Clinical …, 2011 - Elsevier
BACKGROUND & AIMS: It is recommended that patients with chronic hepatitis C virus (HCV)
genotype 3 infections receive 24 weeks of treatment. A rapid virologic response (RVR; at …

Patatin-like phospholipase domain containing 3 sequence variant and hepatocellular carcinoma

SG Corradini, MA Burza, A Molinaro, S Romeo - Hepatology, 2011 - journals.lww.com
We read with interest the reviews by Ghouri et al. 1 and Martinez et al. 2 Ghouri et al.
analyzed the association of nonalcoholic fatty liver disease (NAFLD) with cardiovascular …

The role of mitochondrial genomics in patients with non-alcoholic steatohepatitis (NASH)

R Mehta, K Jeiran, AB Koenig, M Otgonsuren… - BMC medical …, 2016 - Springer
Background Visceral obesity and metabolic syndrome are commonly associated with non-
alcoholic fatty liver disease (NAFLD). The progression of steatosis to NASH depends on a …

[PDF][PDF] DEPDC5 variants increase fibrosis progression in Europeans with chronic hepatitis C virus infection

MA Burza, BM Motta, RM Mancina, P Pingitore… - …, 2016 - Wiley Online Library
Chronic hepatitis C virus (HCV) infection may progress to cirrhosis and hepatocellular
carcinoma (HCC). Recently, two genetic variants, DEPDC5 rs1012068 and MICA …

Polymorphisms in MICA, but not in DEPDC5, HCP5 or PNPLA3, are associated with chronic hepatitis C-related hepatocellular carcinoma

H Hai, A Tamori, LTT Thuy, K Yoshida, A Hagihara… - Scientific Reports, 2017 - nature.com
Recently, the MICA rs2596542 and DEPDC5 rs1012068 variants in Japanese individuals as
well as the HCP5 rs2244546 and PNPLA3 rs738409 variants in European individuals have …

The impact of PNPLA3 (rs738409 C>G) polymorphisms on liver histology and long‐term clinical outcome in chronic hepatitis B patients

WP Brouwer, AJ van der Meer, A Boonstra… - Liver …, 2015 - Wiley Online Library
Abstract Background & Aims We aimed to assess the association between the patatin‐like
phospholipase domain‐containing‐3 (PNPLA 3) I148M polymorphism, liver histology and …