Multifunctional hydrogels based on chitosan, hyaluronic acid and other biological macromolecules for the treatment of inflammatory bowel disease: A review

Y Ouyang, J Zhao, S Wang - International journal of biological …, 2023 - Elsevier
Hydrogel is a three-dimensional network polymer material rich in water. It is widely used in
the biomedical field because of its unique physical and chemical properties and good …

[HTML][HTML] Slimy partners: the mucus barrier and gut microbiome in ulcerative colitis

J Fang, H Wang, Y Zhou, H Zhang, H Zhou… - … & molecular medicine, 2021 - nature.com
Ulcerative colitis (UC) is a chronic recurrent intestinal inflammatory disease characterized by
high incidence and young onset age. Recently, there have been some interesting findings in …

Artificial-enzymes-armed Bifidobacterium longum probiotics for alleviating intestinal inflammation and microbiota dysbiosis

F Cao, L Jin, Y Gao, Y Ding, H Wen, Z Qian… - Nature …, 2023 - nature.com
Inflammatory bowel disease can be caused by the dysfunction of the intestinal mucosal
barrier and dysregulation of gut microbiota. Traditional treatments use drugs to manage …

[HTML][HTML] Two-sample Mendelian randomization analysis investigates causal associations between gut microbial genera and inflammatory bowel disease, and …

B Liu, D Ye, H Yang, J Song, X Sun, Y Mao… - Frontiers in …, 2022 - frontiersin.org
Background Intestinal dysbiosis is associated with inflammatory bowel disease (IBD).
Ulcerative colitis (UC) and Crohn's disease (CD), two subtypes of IBD, are characterized by …

Prevalence of irritable bowel syndrome-type symptoms in patients with inflammatory bowel disease in remission: a systematic review and meta-analysis

KM Fairbrass, SJ Costantino, DJ Gracie… - The lancet …, 2020 - thelancet.com
Background Patients with inflammatory bowel disease (IBD) often report symptoms
compatible with irritable bowel syndrome (IBS), which might have an effect on psychological …

[HTML][HTML] Inflammatory bowel disease: a review of pre-clinical murine models of human disease

B Katsandegwaza, W Horsnell, K Smith - International Journal of …, 2022 - mdpi.com
Crohn's disease (CD) and ulcerative colitis (UC) are both highly inflammatory diseases of
the gastrointestinal tract, collectively known as inflammatory bowel disease (IBD). Although …

IBD disease-modifying therapies: insights from emerging therapeutics

NG Kotla, Y Rochev - Trends in Molecular Medicine, 2023 - cell.com
Inflammatory bowel disease (IBD) pathogenesis is associated with gut mucosal
inflammation, epithelial damage, and dysbiosis leading to a dysregulated gut mucosal …

[HTML][HTML] COVID-19 and immune-mediated inflammatory diseases: effect of disease and treatment on COVID-19 outcomes and vaccine responses

F Fagni, D Simon, K Tascilar, V Schoenau… - The Lancet …, 2021 - thelancet.com
At the beginning of the COVID-19 pandemic, patients with immune-mediated inflammatory
diseases were considered to be at high risk for SARS-CoV-2 infection and the development …

Clinical effects and gut microbiota changes of using probiotics, prebiotics or synbiotics in inflammatory bowel disease: A systematic review and meta-analysis

XF Zhang, XX Guan, YJ Tang, JF Sun, XK Wang… - European journal of …, 2021 - Springer
Purpose Probiotics have been reported to be beneficial for inflammatory bowel disease
(IBD), but the types, number of strains, dosage, and intervention time of probiotics used …

Advances in the colon-targeted chitosan based multiunit drug delivery systems for the treatment of inflammatory bowel disease

N Kulkarni, P Jain, A Shindikar, P Suryawanshi… - Carbohydrate …, 2022 - Elsevier
Chitosan is the polymer of choice for delivery of the active moieties to the colon due to its
cationic nature that enables strong mucosal attachment. Chitosan is explored for …