Transgenic mouse models have contributed considerably to our understanding of the
cellular and molecular mechanisms by which androgens control spermatogenesis. Cell …

This review aims to evaluate the contribution of individual cell-selective knockout models to
our current understanding of androgen action. Cre/loxP technology has allowed the …

Evidence regarding the components of the renin–angiotensin (Ang) system suggests that
this system plays an important role in male reproduction. However, there are few data …

Evidence from several models of hormone depletion and/or replacement and from knockout
animals points to a key role of androgens in the control of spermatogenesis. In testes of mice …

Androgen-mediated wolffian duct (WD) development is programmed between embryonic d
15.5 (e15. 5) and 17.5 in male rats, and WD differentiation has been shown to be more …

Male infertility is often related to reproductive age couples experiencing fertility-related
issues. Men may have fertility problems associated with reversible testicular damage …

Nephrin and podocin are known to be closely related to the pharmacological effects of
angiotensin‐II receptor blocker (ARB). The objectives of this study were to investigate the …

Introduction: Obesity is defined as chronic low-grade inflammation which is manifestation of
the cellular response to a variety of stressful situations leading to organ and tissue damage …

Diabetes-related reproductive dysfunction is considered a major health concern. Its
pathogenesis is closely linked to oxidative stress. Antox is a combination of antioxidants …

Secondary hypogonadism is a consequence of congenital or acquired diseases that affect
the hypothalamus and/or pituitary gland, impairing secretion of gonadotrophin-releasing …