Dataset: Impact of β-Galactosylceramidase Overexpression on the Protein Profile of Braf (V600E) Mutated Melanoma Cells
β-Galactosylceramidase (GALC) is a lysosomal enzyme involved in sphingolipid metabolism
by removing β-galactosyl moieties from β-galactosyl ceramide and β-galactosyl …
by removing β-galactosyl moieties from β-galactosyl ceramide and β-galactosyl …
Combined therapy of dabrafenib and an anti-HER2 antibody–drug conjugate for advanced BRAF-mutant melanoma
W Li, C Zheng, X Xu, Y Xia, K Zhang, A Huang… - Cellular & Molecular …, 2024 - Springer
Background Melanoma is the most lethal skin cancer characterized by its high metastatic
potential. In the past decade, targeted and immunotherapy have brought revolutionary …
potential. In the past decade, targeted and immunotherapy have brought revolutionary …
Proteomic Analysis Highlights the Impact of the Sphingolipid Metabolizing Enzyme β-Galactosylceramidase on Mitochondrial Plasticity in Human Melanoma
D Capoferri, L Mignani, M Manfredi… - International Journal of …, 2024 - mdpi.com
Mitochondrial plasticity, marked by a dynamism between glycolysis and oxidative
phosphorylation due to adaptation to genetic and microenvironmental alterations …
phosphorylation due to adaptation to genetic and microenvironmental alterations …
ROLE OF SPHINGOLIPID METABOLISM IN MELANOMA PROGRESSION
M Corli - 2024 - iris.unibs.it
Sphingolipids and their metabolizing enzymes are involved in a variety of physiological and
pathological conditions. During my PhD program I focused my research activity on the role of …
pathological conditions. During my PhD program I focused my research activity on the role of …