Phenomapping in heart failure with preserved ejection fraction: insights, limitations, and future directions
Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous entity with
complex pathophysiology and manifestations. Phenomapping is the process of applying …
complex pathophysiology and manifestations. Phenomapping is the process of applying …
Endocrine functions of the heart: from bench to bedside
Heart has a recognized endocrine function as it produces several biologically active
substances with hormonal properties. Among these hormones, the natriuretic peptide (NP) …
substances with hormonal properties. Among these hormones, the natriuretic peptide (NP) …
Natriuretic peptides: it is time for guided therapeutic strategies based on their molecular mechanisms
Natriuretic peptides (NPs) are the principal expression products of the endocrine function of
the heart. They exert several beneficial effects, mostly mediated through guanylate cyclase …
the heart. They exert several beneficial effects, mostly mediated through guanylate cyclase …
[HTML][HTML] The year in cardiovascular medicine 2021: heart failure and cardiomyopathies
J Bauersachs, RA de Boer, JA Lindenfeld… - Cardiologia …, 2022 - hrcak.srce.hr
Sažetak In the year 2021, the universal definition and classification of heart failure (HF) was
published that defines HF as a clinical syndrome with symptoms and/or signs caused by a …
published that defines HF as a clinical syndrome with symptoms and/or signs caused by a …
Sacubitril/valsartan as a therapeutic tool across the range of heart failure phenotypes and ejection fraction spectrum
Heart failure (HF) is a complex syndrome caused by a variety of structural or functional
cardiac abnormalities as a consequence of several involved pathophysiological pathways …
cardiac abnormalities as a consequence of several involved pathophysiological pathways …
Effect of sacubitril/valsartan combined with dapagliflozin on long-term cardiac mortality in heart failure with reduced ejection fraction
U Karabulut, K Keskin, D Karabulut, E Yiğit… - Angiology, 2022 - journals.sagepub.com
The angiotensin receptor–neprilysin inhibitor (ARNI) sacubitril/valsartan and sodium-
glucose cotransporter-2 (SGLT-2) inhibitor dapagliflozin have been shown to reduce …
glucose cotransporter-2 (SGLT-2) inhibitor dapagliflozin have been shown to reduce …
Real-world comparative effectiveness of ARNI versus ACEi/ARB in HF with reduced or mildly reduced ejection fraction
M Fu, A Pivodic, O Käck, M Costa-Scharplatz… - Clinical Research in …, 2023 - Springer
Aims Sacubitril/valsartan is a first-in-class angiotensin receptor–neprilysin inhibitor (ARNI)
with a class-1 guideline recommendation. We assessed the real-world effectiveness of ARNI …
with a class-1 guideline recommendation. We assessed the real-world effectiveness of ARNI …
The effect of sacubitril/valsartan treatment on cardiac and renal functions of a patient with cardiorenal syndrome type 4 and Stage 5 ckd after more than three years of …
S Cheng, T Zhou, L Yu, Y Chen, Z Zhang… - Frontiers in …, 2022 - frontiersin.org
It is difficult to treat cardiorenal syndrome (CRS) in clinical practice, which is the common
reason for the death of patients. This report aimed to describe the effects of …
reason for the death of patients. This report aimed to describe the effects of …
Heart failure with preserved ejection fraction: key stumbling blocks for experimental drugs in clinical trials
A Lloji, J Sreenivasan, J Novograd… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Heart failure with preserved ejection fraction (HFpEF) is a disease with a high
prevalence. Accounting for more than 50% of all heart failure cases, it carries a significant …
prevalence. Accounting for more than 50% of all heart failure cases, it carries a significant …
Sacubitril/valsartan in heart failure and beyond—from molecular mechanisms to clinical relevance
As the ultimate pathophysiological event, heart failure (HF) may arise from various
cardiovascular (CV) conditions, including sustained pressure/volume overload of the left …
cardiovascular (CV) conditions, including sustained pressure/volume overload of the left …