Mechanisms, management, and treatment of fibrosis in patients with inflammatory bowel diseases

F Rieder, C Fiocchi, G Rogler - Gastroenterology, 2017 - Elsevier
In the last 10 years, we have learned much about the pathogenesis, diagnosis, and
management of intestinal fibrosis in patients with inflammatory bowel diseases. Just a …

The impact of the microbiota on the pathogenesis of IBD: lessons from mouse infection models

S Nell, S Suerbaum, C Josenhans - Nature Reviews Microbiology, 2010 - nature.com
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is a
major human health problem. The bacteria that live in the gut play an important part in the …

A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes

BP Willing, J Dicksved, J Halfvarson, AF Andersson… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS:: The composition of the gastrointestinal microbiota is thought to
have an important role in the etiology of inflammatory bowel diseases (IBDs) such as …

A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3

A Murthy, Y Li, I Peng, M Reichelt, AK Katakam… - Nature, 2014 - nature.com
Crohn's disease is a debilitating inflammatory bowel disease (IBD) that can involve the
entire digestive tract. A single-nucleotide polymorphism (SNP) encoding a missense variant …

Novel mechanisms and clinical trial endpoints in intestinal fibrosis

J Wang, S Lin, JM Brown, D van Wagoner… - Immunological …, 2021 - Wiley Online Library
The incidence of inflammatory bowel diseases (IBD) worldwide has resulted in a global
public health challenge. Intestinal fibrosis leading to stricture formation and bowel …

Characteristics of fecal and mucosa-associated microbiota in Chinese patients with inflammatory bowel disease

L Chen, W Wang, R Zhou, SC Ng, J Li, M Huang… - Medicine, 2014 - journals.lww.com
The intestinal microbiota plays an important role in the pathogenesis of inflammatory bowel
disease (IBD), and geographical and genetic backgrounds impact the composition of the …

Dysbiotic microbiota interactions in Crohn's disease

E Caparrós, R Wiest, M Scharl, G Rogler… - Gut …, 2021 - Taylor & Francis
Crohn's disease (CD) is a major form of inflammatory bowel disease characterized by
transmural inflammation along the alimentary tract. Changes in the microbial composition …

Intestinal fibrosis in IBD—a dynamic, multifactorial process

F Rieder, C Fiocchi - Nature reviews Gastroenterology & hepatology, 2009 - nature.com
Intestinal fibrosis is a common and potentially serious complication of IBD that results from
the reaction of intestinal tissue to the damage inflicted by chronic inflammation. The …

A unique megaplasmid contributes to stress tolerance and pathogenicity of an emergent Salmonella enterica serovar Infantis strain

G Aviv, K Tsyba, N Steck… - Environmental …, 2014 - Wiley Online Library
Of all known S almonella enterica serovars, S. Infantis is one of the most commonly isolated
and has been recently emerging worldwide. To understand the recent emergence of S …

In Vitro and In Vivo Antibacterial Activity of Punica granatum Peel Ethanol Extract against Salmonella

JG Choi, OH Kang, YS Lee, HS Chae… - Evidence‐Based …, 2011 - Wiley Online Library
Punica granatum is commonly used in Korea as a traditional medicine for the treatment of
pathogenic bacteria. In this study, we investigated the in vitro and in vivo antimicrobial …