The gut microbiota is critical to human health, such as digesting nutrients, forming the
intestinal epithelial barrier, regulating immune function, producing vitamins and hormones …

The global population is aging and age-related cardiovascular disease is increasing. Even
after controlling for cardiovascular risk factors, readmission and mortality rates remain high …

Bile acids regulate nutrient absorption and mitochondrial function, they establish and
maintain gut microbial community composition and mediate inflammation, and they serve as …

Dicarboxylic fatty acids are generated in the liver and kidney in a minor pathway called fatty
acid ω-oxidation. The effects of consuming dicarboxylic fatty acids as an alternative source …

Bile acids (BAs), key regulators in the metabolic network, are not only involved in lipid
digestion and absorption but also serve as potential therapeutic targets for metabolic …

Bile acids are specific and quantitatively important organic components of bile, which are
synthesized by hepatocytes from cholesterol and are involved in the osmotic process that …

Ambient ozone (O 3) pollution can induce respiratory and cardiovascular toxicity. However,
its impact on the metabolome and the underlying mechanisms remain unclear. This study …

Affecting approximately 25% of the global population, steatotic liver disease (SLD) poses a
significant health concern. SLD ranges from simple steatosis to metabolic dysfunction …

The association between gut microbiota and the development of heart failure has become a
research hotspot in recent years and the impact of gut microbiota on heart failure has …

Heart failure (HF) is a leading cause of mortality worldwide. The pathogenesis of HF is
complex and has not yet been fully elucidated, which has slowed drug development and …