The Structural and Molecular Underpinnings of Gametogenesis in Toxoplasma gondii

R Tomasina, ME Francia - Frontiers in cellular and infection …, 2020 - frontiersin.org
Toxoplasma gondii is a widely prevalent protozoan parasite member of the phylum
Apicomplexa. It causes disease in humans with clinical outcomes ranging from an …

Basal body structure and composition in the apicomplexans Toxoplasma and Plasmodium

ME Francia, JF Dubremetz, NS Morrissette - Cilia, 2015 - Springer
The phylum Apicomplexa encompasses numerous important human and animal disease-
causing parasites, including the Plasmodium species, and Toxoplasma gondii, causative …

The tubulin superfamily in apicomplexan parasites

N Morrissette, I Abbaali, C Ramakrishnan, AB Hehl - Microorganisms, 2023 - mdpi.com
Microtubules and specialized microtubule-containing structures are assembled from
tubulins, an ancient superfamily of essential eukaryotic proteins. Here, we use bioinformatic …

The tubulin database: Linking mutations, modifications, ligands and local interactions

I Abbaali, D Truong, SD Day, F Mushayeed, B Ganesh… - Plos one, 2023 - journals.plos.org
Microtubules are polymeric filaments, constructed of α-β tubulin heterodimers that underlie
critical subcellular structures in eukaryotic organisms. Four homologous proteins (γ-, δ-, ε …

The tubulin mutation database: A resource for the cytoskeleton community

CL Pham, NS Morrissette - Cytoskeleton, 2019 - Wiley Online Library
Over the last 40 years, the phenotypic consequences of point mutations to tubulin genes
have been described in a wide variety of eukaryotes. A publicly available web‐based …

Electron tomography study of isolated human centrioles

R Ibrahim, C Messaoudi, FJ Chichon… - Microscopy research …, 2009 - Wiley Online Library
Centrioles are components of the centrosome, which is present in most eukaryotic cells
(from protozoa to mammals). They organize the microtubule skeleton during interphase and …

Role of CAP350 in centriolar tubule stability and centriole assembly

M Le Clech - PLoS One, 2008 - journals.plos.org
Background Centrioles are microtubule-based cylindrical structures composed of nine triplet
tubules and are required for the formation of the centrosome, flagella and cilia. Despite …

New insights into the cell biology of insect axonemes

C Mencarelli, P Lupetti, R Dallai - International review of cell and molecular …, 2008 - Elsevier
Insects do not possess ciliated epithelia, and cilia/flagella are present in the sperm tail and—
as modified cilia—in mechano‐and chemosensory neurons. The core cytoskeletal …

Mutations in α-tubulin promote basal body maturation and flagellar assembly in the absence of δ-tubulin

S Fromherz, TH Giddings Jr… - Journal of cell …, 2004 - journals.biologists.com
We have isolated suppressors of the deletion allele of δ-tubulin, uni3-1, in the biflagellate
green alga Chlamydomonas reinhardtii. The deletion of δ-tubulin produces cells that …

The cilioprotist cytoskeleton, a model for understanding how cell architecture and pattern are specified: recent discoveries from ciliates and comparable model …

LA Hufnagel - Cytoskeleton: Methods and Protocols, 2022 - Springer
The cytoskeletons of eukaryotic, cilioprotist microorganisms are complex, highly patterned,
and diverse, reflecting the varied and elaborate swimming, feeding, reproductive, and …