Deep brain stimulation and intrathecal/intraventricular baclofen for glutaric aciduria type 1: a scoping review, individual patient data analysis, and clinical trials review

NA Shlobin, K Hofmann, RF Keating… - Journal of Inherited …, 2023 - Wiley Online Library
Abstract Glutaric aciduria type 1 (GA1) is an autosomal recessive disease frequently leading
to dystonia. Deep brain stimulation (DBS), intrathecal baclofen (ITB), and intraventricular …

[HTML][HTML] Barriers to epilepsy surgery in pediatric patients: a scoping review

R Hatoum, N Nathoo-Khedri, NA Shlobin, A Wang… - Seizure, 2022 - Elsevier
Rationale Up to 40% of pediatric epilepsy cases are drug-resistant and associated with
neurocognitive, psychosocial, developmental comorbidities, and risk of early mortality …

Current principles in the management of drug-resistant epilepsy

NA Shlobin, JW Sander - CNS drugs, 2022 - Springer
Drug-resistant epilepsy is associated with poor health outcomes and increased economic
burden. In the last three decades, various new antiseizure medications have been …

Ethical considerations in surgical decompression for stroke

NA Shlobin, JR Clark, JM Campbell, M Bernstein… - Stroke, 2022 - Am Heart Assoc
Stroke is a major cause of morbidity and mortality. Neurosurgical decompression is often
considered for the treatment of malignant infarcts and intraparenchymal hemorrhages, but …

Health literacy in neurosurgery: a scoping review

NA Shlobin, J Huang, S Lam - World neurosurgery, 2022 - Elsevier
Objective Low health literacy is prevalent and associated with suboptimal health outcomes.
In neurosurgery, social determinants of health are increasingly recognized as factors …

Disability or death: a focused review of informed consent in pediatric neurosurgery

NA Shlobin, JPG Kolcun, BD Leland… - Seminars in pediatric …, 2023 - Elsevier
The management of pediatric neurosurgical disease often requires families to choose
between long-term disability and premature death. This decision-making is codified by …

Deep brain stimulation of the Centromedian nucleus of the thalamus for Lennox-Gastaut syndrome: a systematic review and individual patient data analysis

NA Shlobin, K Hofmann, NT Cohen, MZ Koubeissi… - …, 2023 - journals.lww.com
BACKGROUND: Lennox-Gastaut syndrome (LGS) is a severe childhood-onset
pharmacoresistant epilepsy. Deep brain stimulation (DBS) of the centromedian nucleus of …

Ethics of Transitioning from Curative Care to Palliative Care: Potential Conflicts of Interest Using the Example of Neurosurgery

NA Shlobin, M Sheldon, M Bernstein - World neurosurgery, 2022 - Elsevier
Background Neurosurgical conditions are often incurable and lead to disability, severe
physical symptoms, and distress for patients and families. Neurosurgeons may be …

Ethical Considerations in the Treatment of Cerebrovascular Disease

NA Shlobin - Current Treatment Options in Neurology, 2024 - Springer
Abstract Purpose of Review To care for patients with cerebrovascular disease (CVD),
neurointerventionalists, intensivists, and other healthcare providers must be equipped to …

Delays in the diagnosis and surgical treatment of drug‐resistant epilepsy: A cohort study

JM Campbell, S Yost, D Gautam, A Herich, D Botros… - …, 2024 - Wiley Online Library
Objective Delay in referral for epilepsy surgery of patients with drug‐resistant epilepsy
(DRE) is associated with decreased quality of life, worse surgical outcomes, and increased …