Cyanovirin-N inhibits hepatitis C virus entry by binding to envelope protein glycans

F Helle, C Wychowski, N Vu-Dac, KR Gustafson… - Journal of Biological …, 2006 - ASBMB
Inhibition of viruses at the stage of viral entry provides a route for therapeutic intervention.
Because of difficulties in propagating hepatitis C virus (HCV) in cell culture, entry inhibitors …

Antiretroviral therapy and drug resistance in human immunodeficiency virus type 2 infection

L Menéndez-Arias, M Álvarez - Antiviral research, 2014 - Elsevier
One to two million people worldwide are infected with the human immunodeficiency virus
type 2 (HIV-2), with highest prevalences in West African countries, but also present in …

[PDF][PDF] Probing protein–carbohydrate interactions with microarrays of synthetic oligosaccharides

DM Ratner, EW Adams, J Su, BR O'Keefe… - …, 2004 - academia.edu
Formerly a™ neglected dimension∫ of biochemistry, recent years have seen growing
interest in studying the biological function of carbohydrates and glycoconjugates. An …

The isolation of water-soluble natural products–challenges, strategies and perspectives

RGS Berlinck, CM Crnkovic, JR Gubiani… - Natural Product …, 2022 - pubs.rsc.org
Covering period: up to 2019 Water-soluble natural products constitute a relevant group of
secondary metabolites notably known for presenting potent biological activities. Examples …

Antimicrobial peptides from amphibian skin potently inhibit human immunodeficiency virus infection and transfer of virus from dendritic cells to T cells

SE VanCompernolle, RJ Taylor… - Journal of …, 2005 - Am Soc Microbiol
Topical antimicrobicides hold great promise in reducing human immunodeficiency virus
(HIV) transmission. Amphibian skin provides a rich source of broad-spectrum antimicrobial …

Role of marine natural products in the genesis of antiviral agents

V Gogineni, RF Schinazi, MT Hamann - Chemical reviews, 2015 - ACS Publications
Mammals have complex biological systems and are constantly prone to infections by a wide
array of bacteria, fungi, viruses, and parasites, a significant challenge to the constant …

Microbicide drug candidates to prevent HIV infection

J Balzarini, L Van Damme - The Lancet, 2007 - thelancet.com
Summary 25 years after the first HIV/AIDS cases emerged in 1981, the disease continues to
spread worldwide, with about 15 000 new infections every day. Although highly active …

Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides

I Botos, BR O'Keefe, SR Shenoy, LK Cartner… - Journal of Biological …, 2002 - ASBMB
The development of anti-human immunodeficiency virus (HIV) microbicides for either topical
or ex vivo use is of considerable interest, mainly due to the difficulties in creating a vaccine …

Bioactive compounds from microalgae: Current development and prospects

W Fu, DR Nelson, Z Yi, M Xu, B Khraiwesh… - Studies in natural …, 2017 - Elsevier
Microalgae make up the largest and likely most diverse group of photosynthetic organisms
in freshwater and marine systems. As new technologies are emerging for the study of …

Human lectins and their roles in viral infections

CP Mason, AW Tarr - Molecules, 2015 - mdpi.com
Innate recognition of virus proteins is an important component of the immune response to
viral pathogens. A component of this immune recognition is the family of lectins; pattern …