[HTML][HTML] Inflammation and cardiovascular disease: From mechanisms to therapeutics

A Alfaddagh, SS Martin, TM Leucker, ED Michos… - American journal of …, 2020 - Elsevier
Inflammation constitutes a complex, highly conserved cascade of molecular and cellular
events. Inflammation has been labeled as “the fire within,” is highly regulated, and is critical …

[HTML][HTML] The progress of gut microbiome research related to brain disorders

S Zhu, Y Jiang, K Xu, M Cui, W Ye, G Zhao… - Journal of …, 2020 - Springer
There is increasing evidence showing that the dynamic changes in the gut microbiota can
alter brain physiology and behavior. Cognition was originally thought to be regulated only by …

[HTML][HTML] The gut microbiome in coronary artery disease and heart failure: Current knowledge and future directions

M Trøseid, GØ Andersen, K Broch, JR Hov - EBioMedicine, 2020 - thelancet.com
Host-microbiota interactions involving inflammatory and metabolic pathways have been
linked to the pathogenesis of multiple immune-mediated diseases and metabolic conditions …

[HTML][HTML] Gut microbiota-dependent marker TMAO in promoting cardiovascular disease: inflammation mechanism, clinical prognostic, and potential as a therapeutic …

S Yang, X Li, F Yang, R Zhao, X Pan, J Liang… - Frontiers in …, 2019 - frontiersin.org
Cardiovascular disease (CVD) is the leading cause of death worldwide, especially in
developed countries, and atherosclerosis (AS) is the common pathological basis of many …

Gut microbiota metabolites and risk of major adverse cardiovascular disease events and death: a systematic review and meta‐analysis of prospective studies

Y Heianza, W Ma, JAE Manson… - Journal of the American …, 2017 - Am Heart Assoc
Background Gut microbial metabolites have been implicated as novel risk factors for
cardiovascular events and premature death. The strength and consistency of associations …

Microbial modulation of cardiovascular disease

JM Brown, SL Hazen - Nature Reviews Microbiology, 2018 - nature.com
Although diet has long been known to contribute to the pathogenesis of cardiovascular
disease (CVD), research over the past decade has revealed an unexpected interplay …

Role of gut microbiota in atherosclerosis

AL Jonsson, F Bäckhed - Nature Reviews Cardiology, 2017 - nature.com
Infections have been linked to the development of cardiovascular disease and
atherosclerosis. Findings from the past decade have identified microbial ecosystems …

Trimethylamine‐N‐oxide (TMAO) response to animal source foods varies among healthy young men and is influenced by their gut microbiota composition: A …

CE Cho, S Taesuwan, OV Malysheva… - Molecular nutrition & …, 2017 - Wiley Online Library
Scope Trimethylamine‐N‐oxide (TMAO), a metabolite linked to the gut microbiota, is
associated with excess risk of heart disease. We hypothesized that (i) TMAO response to …

Intestinal microbiome and fitness in kidney disease

B Meijers, P Evenepoel, HJ Anders - Nature reviews nephrology, 2019 - nature.com
Environmental changes can induce diversity shifts within ecosystems that affect interactions
between species. Similarly, the development of kidney disease induces shifts within the …

Trimethylamine N‐oxide generated by the gut microbiota is associated with vascular inflammation: new insights into atherosclerosis

Y Liu, M Dai - Mediators of inflammation, 2020 - Wiley Online Library
Trimethylamine N‐oxide (TMAO) is a biologically active molecule generated by the gut
microbiota. Accumulating evidences have indicated a close association between high …