[PDF][PDF] 基于细胞膜损伤机制的抗菌肽结构优化研究进展

张良, 潘滢浩, 袁瑜, 黄波, 孟广鹏, 李元波, 周琳 - 中国抗生素杂志, 2023 - zgkss.com.cn
抗菌肽相比传统抗生素, 具有广谱杀菌, 对多重耐药菌有效, 生物相容性好等优点. 近年来,
抗菌肽独特的细胞膜靶向作用机制得到了深入研究, 基于此机制上的结构优化策略也成为了近期 …

Deciphering Structure-Function Relationship Unveils Salt-Resistant Mode of Action of a Potent MRSA-Inhibiting Antimicrobial Peptide, RR14

CC Kao, TL Lin, CJ Lin, TS Tseng - Journal of Bacteriology, 2022 - Am Soc Microbiol
Multidrug-resistant (MDR) bacteria lead to considerable morbidity and mortality, threatening
public health worldwide. In particular, infections of methicillin-resistant Staphylococcus …

Evaluation of the Synthetic Multifunctional Peptide Hp-MAP3 Derivative of Temporin-PTa

PS Silva, AS Guindo, PHC Oliveira, LFRN de Moraes… - Toxins, 2023 - mdpi.com
In recent years, antimicrobial peptides isolated from amphibian toxins have gained attention
as new multifunctional drugs interacting with different molecular targets. We aimed to …

Phytochemicals as Antimicrobial Agents: Applications in Infectious Diseases

OT Oladele, MO Aladejana, TS Adewole… - … of Research on …, 2022 - igi-global.com
Microbial infections and antibiotic resistance are two of the most serious threats to society's
health today. Millions of people die each year as a result of microbial infections. In 2020, the …

[HTML][HTML] An Insight into All Tested Small Molecules against Fusarium oxysporum f. sp. Albedinis: A Comparative Review

Y Kaddouri, R Benabbes, S Ouahhoud, M Abdellattif… - Molecules, 2022 - mdpi.com
Bayoud disease affects date palms in North Africa and the Middle East, and many
researchers have used various methods to fight it. One of those methods is the chemical use …

Combined Therapy of Probiotic Microcapsules and Bomidin in Vibrio parahaemolyticus–Infected Rats

T Zhou, M Liu, J Pan, J Ren, F Tang, J Dai, F Xue, D Ji - Life, 2022 - mdpi.com
Background: With the discovery of more and more drug–resistant bacterial strains, there is
an urgent need for safer and more effective alternative treatments. In this study, antibacterial …

Antibacterial and Antiviral Properties of Chenopodin-Derived Synthetic Peptides

N Espinosa de los Monteros Silva, C Proaño Bolaños… - 2024 - repositorio.ikiam.edu.ec
Antimicrobial peptides have been developed based on plant-derived molecular scaffolds for
the treatment of infectious diseases. Chenopodin is an abundant seed storage protein in …

Antimicrobial peptide AP2 ameliorates Salmonella Typhimurium infection by modulating gut microbiota

L Li, A Fu, Q Mo, Y Wan, Y Zhou, Z Zeng, A Shan… - 2024 - researchsquare.com
Endogenous antimicrobial peptides/proteins contribute to reshape a healthy gut microbiota
which play benefit roles in anti-inflammation and pathogen colonization resistance …

Insights into the mechanism (s) of action of the membrane-active host-defence Esc peptides on model and living systems

E Puglisi - 2023 - iris.uniroma1.it
The increase in bacterial strains resistant to conventional antibiotics is an alarming problem
for human health and could cause future pandemics. Among such bacterial pathogens …

Antimicrobial Peptides: Principal Defense Constituents of Silk Worms-A Review

JA Sangma, BP Baroowa, YR Singh, P Choudhury - 2023 - indianjournals.com
Insect has a highly developed innate immune system consisting of cellular and humoral
responses. Antimicrobial peptides (AMPs) are the important components of the insect's …