Modulation of atherosclerosis‐related signaling pathways by Chinese herbal extracts: Recent evidence and perspectives

C Liu, X Guo, X Zhang - Phytotherapy Research, 2024 - Wiley Online Library
Atherosclerotic cardiovascular disease remains a preeminent cause of morbidity and
mortality globally. The onset of atherosclerosis underpins the emergence of ischemic …

[HTML][HTML] Targeting of G-protein coupled receptor 40 alleviates airway hyperresponsiveness through RhoA/ROCK1 signaling pathway in obese asthmatic mice

X Lin, L Wang, X Lu, Y Zhang, R Zheng, R Chen… - Respiratory …, 2023 - Springer
Obesity increases the severity of airway hyperresponsiveness (AHR) in individuals with
asthma, but the mechanism is not well elucidated. G-protein coupled receptor 40 (GPR40) …

[HTML][HTML] Regulation of the Hippo/YAP axis by CXCR7 in the tumorigenesis of gastric cancer

T Wang, D Wang, Y Sun, T Zhuang, X Li… - Journal of Experimental …, 2023 - Springer
Abstract Background The Hippo pathway is crucial in organ size control and tumorigenesis.
Dysregulation of the Hippo/YAP axis is commonly observed in gastric cancer, while effective …

[HTML][HTML] Rho kinase inhibitor Y-27632 downregulates IL-1β expression in mice with experimental autoimmune myocarditis

Y Li, G Gao, Y Han, B Xiao, L Shen, X Yang, Y Liu… - Scientific Reports, 2024 - nature.com
Autoimmune myocarditis is the limited or diffuse inflammation of the myocardium due to
dysfunctional cellular and humoral immunity mechanisms. We constructed mouse models of …

Immunometabolism in Health and Disease

M Doroudchi, K Kalantar - Endocrine, Metabolic & Immune …, 2022 - ingentaconnect.com
The immune system is one of the most complex, dynamic and versatile systems of the body.
Although the main function of this system is defense against pathogens, its interaction with …

ROCK inhibitor Y-27632 down-regulates Il-1β expression in mice with experimental autoimmune myocarditis

Y Li, G Gao, Y Han, B Xiao, L Shen, X Yang, Y Liu… - 2023 - researchsquare.com
Autoimmune myocarditis is a limited or diffuse inflammation of the myocardium brought on
by dysfunction in the normal function of cellular and humoral immunity of the body. Mouse …