Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis

A Sierra, O Abiega, A Shahraz… - Frontiers in cellular …, 2013 - frontiersin.org
Microglia are the resident brain macrophages and they have been traditionally studied as
orchestrators of the brain inflammatory response during infections and disease. In addition …

Recent advances in cancer therapeutic copper-based nanomaterials for antitumor therapy

R Aishajiang, Z Liu, T Wang, L Zhou, D Yu - Molecules, 2023 - mdpi.com
Copper serves as a vital microelement which is widely present in the biosystem, functioning
as multi-enzyme active site, including oxidative stress, lipid oxidation and energy …

Curcumin in cancer therapy: Exploring molecular mechanisms and overcoming clinical challenges

W Wang, M Li, L Wang, L Chen, BC Goh - Cancer Letters, 2023 - Elsevier
Cancer poses a significant global health burden, necessitating the widespread use of
chemotherapy and radiotherapy as conventional frontline interventions. Although targeted …

The emerging role of paraptosis in tumor cell biology: Perspectives for cancer prevention and therapy with natural compounds

F Fontana, M Raimondi, M Marzagalli… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Standard anti-cancer therapies promote tumor growth suppression mainly via induction of
apoptosis. However, in most cases cancer cells acquire the ability to escape apoptotic cell …

Hormonal control of cell division and elongation along differentiation trajectories in roots

H Takatsuka, M Umeda - Journal of experimental botany, 2014 - academic.oup.com
The continuous development of roots is supported by a sustainable system for cell
production and growth at the root tip. In the stem cell niche that consists of a quiescent …

Paraptosis: a unique cell death mode for targeting cancer

S Hanson, A Dharan, J PV, S Pal, BG Nair… - Frontiers in …, 2023 - frontiersin.org
Programmed cell death (PCD) is the universal process that maintains cellular homeostasis
and regulates all living systems' development, health and disease. Out of all, apoptosis is …

Paraptosis in the anti-cancer arsenal of natural products

D Lee, IY Kim, S Saha, KS Choi - Pharmacology & therapeutics, 2016 - Elsevier
Given the problems with malignant cancer cells showing innate and acquired resistance to
apoptosis, we need alternative means to induce cell death in cancer. Paraptosis is a type of …

DNA damage-induced cell death: lessons from the central nervous system

HL Borges, R Linden, JYJ Wang - Cell research, 2008 - nature.com
DNA damage can, but does not always, induce cell death. While several pathways linking
DNA damage signals to mitochondria-dependent and-independent death machineries have …

Ionizing Radiation-Induced Responses in Human Cells with Differing TP53 Status

R Mirzayans, B Andrais, A Scott, YW Wang… - International journal of …, 2013 - mdpi.com
Ionizing radiation triggers diverse responses in human cells encompassing apoptosis,
necrosis, stress-induced premature senescence (SIPS), autophagy, and endopolyploidy (eg …

Evidence for mobile phone radiation exposure effects on reproductive pattern of male rats: role of ROS

KK Kesari, J Behari - Electromagnetic biology and medicine, 2012 - Taylor & Francis
The relationship between radiofrequency electromagnetic fields emitted from mobile phone
and infertility is a matter of continuing debate. It is postulated that these radiations may affect …