Alzheimer's therapeutic development: shifting neurodegeneration to neuroregeneration
MK Sun, DL Alkon - Trends in Pharmacological Sciences, 2024 - cell.com
Abstract Alzheimer's disease (AD), similar to AD-related dementias, is characterized by
impaired/lost neuronal structures and functions due to a long progression of …
impaired/lost neuronal structures and functions due to a long progression of …
Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer's disease
The risk of developing Alzheimer's disease (AD) significantly increases in individuals
carrying the APOEε4 allele. Elderly cognitively healthy individuals with APOEε4 also exist …
carrying the APOEε4 allele. Elderly cognitively healthy individuals with APOEε4 also exist …
Nicotine suppresses crystalline silica‐induced astrocyte activation and neuronal death by inhibiting NF‐κB in the mouse hippocampus
H Cao, B Li, M Mu, S Li, H Chen, H Tao… - CNS Neuroscience …, 2024 - Wiley Online Library
Aims Exposure to crystalline silica (CS) in occupational settings induces chronic
inflammation in the respiratory system and, potentially, the brain. Some workers are …
inflammation in the respiratory system and, potentially, the brain. Some workers are …
[HTML][HTML] Genetic Contributions to Recovery following Brain Trauma: A Narrative Review
D Lakshmipathy, S Rangarajan, A Barreau… - Frontiers in Bioscience …, 2024 - imrpress.com
Traumatic brain injury (TBI) is a frequently encountered form of injury that can have lifelong
implications. Despite advances in prevention, diagnosis, monitoring, and treatment, the …
implications. Despite advances in prevention, diagnosis, monitoring, and treatment, the …
Lipocalin-2 as a mediator of neuroimmune communication
Abstract Lipocalin-2, a neutrophil gelatinase-associated lipocalin, is a 25-kDa secreted
protein implicated in a broad range of inflammatory diseases affecting the brain and …
protein implicated in a broad range of inflammatory diseases affecting the brain and …
Rare genetic variation in Fibronectin 1 (FN1) protects against APOEe4 in Alzheimer's disease
P Bhattarai, TI Gunasekaran, D Reyes-Dumeyer… - bioRxiv, 2024 - biorxiv.org
The risk of developing Alzheimer's disease (AD) significantly increases in individuals
carrying the APOEe4 allele. Elderly cognitively healthy individuals with APOEe4 also exist …
carrying the APOEe4 allele. Elderly cognitively healthy individuals with APOEe4 also exist …
[PDF][PDF] Clinical Epidemiology and APOE Gene Etiology: An Update on Alzheimer's Disease
NA Elhawary, RM Almuqati - Medi Clin Case Rep J, 2024 - researchgate.net
This review discusses the discovery, epidemiology, and gene etiology of Alzheimer's
disease (AD). It also highlights the Alzheimer's gender disparity common comorbid and …
disease (AD). It also highlights the Alzheimer's gender disparity common comorbid and …
Multimodal beneficial effects of BNN27, a Nerve Growth Factor synthetic mimetic, in the 5xFAD mouse model of Alzheimer's Disease
I Charalampopoulos, M Kokkali, K Karali, E Thanou… - 2024 - researchsquare.com
Alzheimer's Disease (AD) is an incurable and debilitating progressive, neurodegenerative
disorder which is the leading cause of dementia worldwide. Neuropathologically, AD is …
disorder which is the leading cause of dementia worldwide. Neuropathologically, AD is …