Maternal pre-pregnancy obesity, offspring cord blood DNA methylation, and offspring cardiometabolic health in early childhood: an epigenome-wide association study
Pre-pregnancy obesity is an established risk factor for adverse sex-specific cardiometabolic
health in offspring. Epigenetic alterations, such as in DNA methylation (DNAm), are a …
health in offspring. Epigenetic alterations, such as in DNA methylation (DNAm), are a …
Mediation by placental DNA methylation of the association of prenatal maternal smoking and birth weight
Prenatal maternal smoking is a risk factor for lower birth weight. We performed epigenome-
wide association analyses of placental DNA methylation (DNAm) at 720,077 cytosine …
wide association analyses of placental DNA methylation (DNAm) at 720,077 cytosine …
A multiple-testing procedure for high-dimensional mediation hypotheses
JY Dai, JL Stanford, M LeBlanc - Journal of the American Statistical …, 2022 - Taylor & Francis
Mediation analysis is of rising interest in epidemiologic studies and clinical trials. Among
existing methods, the joint significance test yields an overly conservative Type I error rate …
existing methods, the joint significance test yields an overly conservative Type I error rate …
Metals exposures and DNA methylation: current evidence and future directions
Abstract Purpose of the Review Exposure to essential and non-essential metals is
widespread. Metals exposure is linked to epigenetic, particularly DNA methylation …
widespread. Metals exposure is linked to epigenetic, particularly DNA methylation …
DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies
Background DNA methylation has been shown to be associated with adiposity in adulthood.
However, whether similar DNA methylation patterns are associated with childhood and …
However, whether similar DNA methylation patterns are associated with childhood and …
Epigenetics in asthma
JL Gomez - Current allergy and asthma reports, 2019 - Springer
Abstract Purpose of Review Asthma is one of the most common chronic respiratory diseases
linked with increased morbidity and healthcare utilization. The underlying …
linked with increased morbidity and healthcare utilization. The underlying …
Epigenetics underlying susceptibility and resilience relating to daily life stress, work stress, and socioeconomic status
MG Gottschalk, K Domschke, MA Schiele - Frontiers in psychiatry, 2020 - frontiersin.org
Susceptibility and resilience to mental disorders result from a complex choreography of
gene–environment interactions with epigenetics at the intersection of external psychological …
gene–environment interactions with epigenetics at the intersection of external psychological …
The association between active tobacco use during pregnancy and growth outcomes of children under five years of age: a systematic review and meta-analysis
D Quelhas, C Kompala, B Wittenbrink, Z Han… - BMC Public Health, 2018 - Springer
Background Despite considerable global efforts to reduce growth faltering in early
childhood, rates of stunting remain high in many regions of the world. Current interventions …
childhood, rates of stunting remain high in many regions of the world. Current interventions …
DNA methylation score as a biomarker in newborns for sustained maternal smoking during pregnancy
Background: Maternal smoking during pregnancy, especially when sustained, leads to
numerous adverse health outcomes in offspring. Pregnant women disproportionately …
numerous adverse health outcomes in offspring. Pregnant women disproportionately …
A cell-type deconvolution meta-analysis of whole blood EWAS reveals lineage-specific smoking-associated DNA methylation changes
Highly reproducible smoking-associated DNA methylation changes in whole blood have
been reported by many Epigenome-Wide-Association Studies (EWAS). These epigenetic …
been reported by many Epigenome-Wide-Association Studies (EWAS). These epigenetic …