[HTML][HTML] From oncolytic peptides to oncolytic polymers: A new paradigm for oncotherapy
H Liu, W Shen, W Liu, Z Yang, D Yin, C Xiao - Bioactive Materials, 2024 - Elsevier
Traditional cancer therapy methods, especially those directed against specific intracellular
targets or signaling pathways, are not powerful enough to overcome tumor heterogeneity …
targets or signaling pathways, are not powerful enough to overcome tumor heterogeneity …
[HTML][HTML] Metformin and its immune-mediated effects in various diseases
I Nojima, J Wada - International journal of molecular sciences, 2023 - mdpi.com
Metformin has been a long-standing prescribed drug for treatment of type 2 diabetes (T2D)
and its beneficial effects on virus infection, autoimmune diseases, aging and cancers are …
and its beneficial effects on virus infection, autoimmune diseases, aging and cancers are …
[HTML][HTML] Implantation of hydrogel-liposome nanoplatform inhibits glioblastoma relapse by inducing ferroptosis
Z Wang, Z Liu, S Wang, X Bing, X Ji, D He… - Asian Journal of …, 2023 - Elsevier
Glioblastoma is acknowledged as the most aggressive cerebral tumor in adults. However,
the efficacy of current standard therapy is seriously undermined by drug resistance and …
the efficacy of current standard therapy is seriously undermined by drug resistance and …
Chemoimmunotherapeutic Nanogel for Pre-and Postsurgical Treatment of Malignant Melanoma by Reprogramming Tumor-Associated Macrophages
L Tang, C Fu, H Liu, Y Yin, Y Cao, J Feng, A Zhang… - Nano Letters, 2024 - ACS Publications
Surgery is the primary method to treat malignant melanoma; however, the residual
microtumors that cannot be resected completely often trigger tumor recurrence, causing …
microtumors that cannot be resected completely often trigger tumor recurrence, causing …
[HTML][HTML] Injectable dexamethasone-loaded peptide hydrogel for therapy of radiation-induced ototoxicity by regulating the mTOR signaling pathway
J Liu, L Zhu, Y Bao, Z Du, L Shi, X Hong, Z Zou… - Journal of Controlled …, 2024 - Elsevier
Radiation-induced ototoxicity is associated with inflammation response and excessive
reactive oxygen species in the cochlea. However, the effectiveness of many drugs in clinical …
reactive oxygen species in the cochlea. However, the effectiveness of many drugs in clinical …
[HTML][HTML] The duality of CXCR3 in glioblastoma: unveiling autocrine and paracrine mechanisms for novel therapeutic approaches
TYH Chan, JSY Wong, KMY Kiang, CWY Sun… - Cell Death & …, 2023 - nature.com
Glioblastoma (GBM) is a highly aggressive brain tumor associated with limited therapeutic
options and a poor prognosis. CXCR3, a chemokine receptor, serves dual autocrine …
options and a poor prognosis. CXCR3, a chemokine receptor, serves dual autocrine …
[HTML][HTML] Bacteria and bacterial components as natural bio-Nanocarriers for drug and gene delivery Systems in Cancer Therapy
R Zong, H Ruan, C Liu, S Fan, J Li - Pharmaceutics, 2023 - mdpi.com
Bacteria and bacterial components possess multifunctional properties, making them
attractive natural bio-nanocarriers for cancer diagnosis and targeted treatment. The inherent …
attractive natural bio-nanocarriers for cancer diagnosis and targeted treatment. The inherent …
Multifunctional porous microspheres encapsulating oncolytic bacterial spores and their potential for cancer immunotherapy
Clostridium novyi-NT (C. novyi-NT) is an anaerobic bacterium that can be used for targeted
cancer therapy because it germinates selectively in the hypoxic regions of tumor tissues …
cancer therapy because it germinates selectively in the hypoxic regions of tumor tissues …
Recent Advances in Biomimetic Strategies for the Immunotherapy of Glioblastoma
H You, S Geng, S Li, M Imani, D Brambilla, T Sun… - Biomaterials, 2024 - Elsevier
Immunotherapy is regarded as one of the most promising approaches for treating tumors,
with a multitude of immunotherapeutic thoughts currently under consideration for the lethal …
with a multitude of immunotherapeutic thoughts currently under consideration for the lethal …
Stemness, invasion, and immunosuppression modulation in recurrent glioblastoma using nanotherapy
S Sarkar, J Greer, NJ Marlowe, A Medvid… - Wiley …, 2024 - Wiley Online Library
The recurrent nature of glioblastoma negatively impacts conventional treatment strategies
leading to a growing need for nanomedicine. Nanotherapeutics, an approach designed to …
leading to a growing need for nanomedicine. Nanotherapeutics, an approach designed to …