Sirtuins in kidney health and disease

L Perico, G Remuzzi, A Benigni - Nature Reviews Nephrology, 2024 - nature.com
Sirtuins (SIRTs) are putative regulators of lifespan in model organisms. Since the initial
discovery that SIRTs could promote longevity in nematodes and flies, the identification of …

Renoprotective mechanisms of exercise training against acute and chronic renal diseases–A perspective based on experimental studies

LFL Malheiro, MM Fernandes, CA Oliveira… - Life Sciences, 2024 - Elsevier
Regular exercise training can lead to several health benefits, reduce mortality risk, and
increase life expectancy. On the other hand, a sedentary lifestyle is a known risk factor for …

[HTML][HTML] Melittin induces autophagy to alleviate chronic renal failure in 5/6-nephrectomized rats and angiotensin II-induced damage in podocytes

Y Zhang, H Xu, H Qiao, Y Zhao… - Nutrition Research and …, 2024 - synapse.koreamed.org
RESULTS In the rat 5/6 Nx, melittin reduced the 24-h urinary protein excretion and the
serum creatinine and blood urea nitrogen levels. Furthermore, the renal pathology was …

[HTML][HTML] 慢性间歇性低氧大鼠肾组织差异蛋白的定量分析: 基于TMTPRM 技术

魏敏, 陈乃洁, 李璟怡, 刘丹, 沈双宏… - Journal of Southern …, 2023 - ncbi.nlm.nih.gov
慢性间歇性低氧大鼠肾组织差异蛋白的定量分析:基于TMTPRM技术- PMC Back to Top Skip
to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …

[HTML][HTML] Anti-influenza drug screening and inhibition of apigetrin on influenza A virus replication via TLR4 and autophagy pathways

M He, Z Ren, MU Goraya, Y Lin, J Ye, R Li… - International …, 2023 - Elsevier
Activation of Toll-like receptor (TLR) 4 plays important roles in the influenza A virus (IAV)
infection. To explore TLR4 inhibitors, 161 traditional Chinese medicines (TCMs) were …

TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease

Y Du, M Wu, S Song, Y Bian, Y Shi - Renal Failure, 2024 - Taylor & Francis
Thioredoxin-interacting protein (TXNIP) is an important regulatory protein for thioredoxin
(TRX) that elicits the generation of reactive oxygen species (ROS) by inhibiting the redox …

慢性间慢性间歇性低氧大鼠肾组织差异蛋白的定量分析歇性低氧大鼠肾组织差异蛋白的定量分析: 基于TMT

魏敏, 陈乃洁, 李璟怡, 刘丹, 沈双宏, 王丰, 吴润华… - europepmc.org
慢性间歇性低氧大鼠肾组织差异蛋白的定量分析:基于TMTPRM技术Quantitative analysis of
differential proteins in renal tissues of rats with chronic intermittent hypoxic exposure based on …

Avaliação do impacto do canabidiol sob o estresse oxidativo na lesão renal aguda induzida por isquemia-reperfusão em ratos wistar adultos

RPN LIMA - 2024 - repositorio.ufpe.br
A lesão renal aguda (LRA) é definida como a redução súbita da função renal. A LRA tem
como característica a possível reversão, porém se não tratada pode evoluir para uma …

[HTML][HTML] Impact of metformin onto ischemia-reperfusion damage of the kidney

SG Ahmed, MM Ramzy… - Minia Journal of …, 2024 - mjmr.journals.ekb.eg
Background: Autophagy means bulk degradation and recycling of cytoplasmic constituents
to maintain cellular homeostasis. In response to stress, autophagy is induced and may …