Many tumor promoters suppress the immune system; however, the direct effect of
immunosuppressants on the tumorigenic pathways of nonimmune cells in solid tissue has …

Phosphorylation of connexin 43 (Cx43) molecules (eg by extracellular signal-regulated
kinase) leads to reductions in gap-junctional intercellular communication (GJIC). GJIC levels …

Methoxychlor (MXC) and vinclozolin (VIN) are well-recognized endocrine disrupting
chemicals known to alter epigenetic regulations and transgenerational inheritance; …

To understand the initiating/promoting actions of pentachlorophenol (PCP), a non-
mutagenic hepatocarcinogen, and its metabolite, tetrachlorohydroquinone (TCHQ), we …

We have developed polyclonal antibodies (SA226P) to a peptide of the human connexin43
(Cx43) protein between amino acids 271 and 288 containing phosphorylated S279 and …

Although the health benefits of dietary antioxidants have been extensively studied, their
potential negative effects remain unclear. L-Ascorbic acid 6-palmitate (AAP), a synthetic …

The methanol extract from the leaves of Petasites japonicus Maxim (PJ) was studied for its
(anti-) mutagenic effect with the SOS chromotest and reverse mutation assay. The (anti-) …

Expression of connexin 43 (Cx43) is correlated with reduced indexes of neoplasia and is
upregulated by cancer-preventive retinoids and carotenoids in nontransformed human and …

Although dieldrin׳ s use in the US was partially banned in the 1970s and its use was
completely eliminated in 1987, dieldrin continues to be a common contaminant at hazardous …

Evidence is mounting supporting a role for oxidative stress in the mechanism of tumour
promotion in response to agents such as 12-O-tetradecanoylphorbol-13-acetate (TPA). In …