Alveolar type II epithelial cells undergo phenotypic changes and establish gap junction
intercellular communication as they reach confluence in primary culture. The pattern of gap …

Expression of connexin 43 (Cx43) is correlated with reduced indexes of neoplasia and is
upregulated by cancer-preventive retinoids and carotenoids in nontransformed human and …

In addition to its antioxidant activity, β-carotene (BC) is known to enhance gap junction
intercellular communication (GJIC) by up-regulation of connexin 43 (Cx43), an action that …

Gap junctional intercellular communication (GJIC) maintains normal growth and
differentiation of cells in a tissue. The intercellular molecules traversing gap junctions are …

Evidence is mounting supporting a role for oxidative stress in the mechanism of tumour
promotion in response to agents such as 12-O-tetradecanoylphorbol-13-acetate (TPA). In …

Gap‐junctional intercellular communication (GJIC) is involved in cellular growth control and
is often reduced in neoplastic cells. In this study, four GJIC‐deficient rat liver epithelial cell …

A new hydrophobic platinum (IV) complex, LA-12, a very efficient anticancer drug lacking
cross-resistance with cisplatin (CDDP), is now being tested in clinical trials. Here we …

The control of cell–cell communication through gap junctions is thought to be crucial in
normal tissue function and during various stages of tumorigenesis. However, few natural …

Gap junctional intercellular communication (GJIC) is thought to be essential for maintaining
cellular homeostasis and growth control. In order to detect any protective agent against …

Chaga mushroom (Inonotus obliquus) has continued to receive attention as a folk medicine
with indications for the treatment of cancers and digestive diseases. The anticarcinogenic …