Non-small cell lung cancer as a chronic disease–A prospective study from the Czech TULUNG registry

M Bratová, B Karlínová, J Skrickova, M Pesek, V Kolek… - in vivo, 2020 - iv.iiarjournals.org
Aim: To compare survival outcomes in patients with non-small cell lung cancer (NSCLC)
treated with modern-era drugs (antifolates, antiangiogenics, tyrosine kinase and anaplastic …

First‐line pembrolizumab vs chemotherapy in metastatic non‐small‐cell lung cancer: KEYNOTE‐024 Japan subset

M Satouchi, K Nosaki, T Takahashi… - Cancer …, 2021 - Wiley Online Library
This prespecified subanalysis of the global, randomized controlled phase III KEYNOTE‐024
study of pembrolizumab vs chemotherapy in previously untreated metastatic non‐small‐cell …

[HTML][HTML] New avenues for the treatment of immunotherapy-resistant pancreatic cancer

LG de Oliveira Silva, FFB Lemos, MS Luz… - World Journal of …, 2024 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) is characterized by its extremely aggressive nature and ranks 14th in
the number of new cancer cases worldwide. However, due to its complexity, it ranks 7th in …

Effectiveness and Safety of PD‐1 Inhibitors' Treatment for Patients with Non‐Small‐Cell Lung Cancer in China: A Real‐World Study

N Wan, Y Chen, L Lu, B Wang, L He… - European Journal of …, 2024 - Wiley Online Library
Background. In this research, programmed cell death protein 1 (PD‐1) inhibitors, including
toripalimab, sintilimab, and camrelizumab, were evaluated for the treatment of non‐small …

[HTML][HTML] Updates and emerging trends in the management of immune-related adverse events associated with immune checkpoint inhibitor therapy

NM La-Beck, J Owoso - Asia-Pacific Journal of Oncology Nursing, 2024 - Elsevier
The rapidly expanding class of therapies targeting immune checkpoints for the treatment of
various cancers now includes 8 clinically approved agents: a LAG-3 inhibitor (relatlimab), a …

Immunotherapy use in older adults with cancer with frailty: A young SIOG review paper

DC Guven, BA Martinez-Cannon, GD Testa… - Journal of Geriatric …, 2024 - Elsevier
Immune checkpoint inhibitors (ICIs) became a treatment option in most tumor types and
improved survival in patients with cancer in the last decade. Older patients with cancer are …

Real-world effectiveness of nivolumab in patients with non-small-cell lung cancer: a systematic review and meta-analysis

YJ Kim, M Oremus, HH Chen, T McFarlane… - Future …, 2020 - Taylor & Francis
Background: The effectiveness of immunotherapies for non-small-cell lung cancer under
real-world clinical settings remains uncertain. Materials & methods: Systematic searches of …

First-line nivolumab plus ipilimumab with or without chemotherapy for Japanese patients with non-small cell lung cancer: LIGHT-NING study

H Imai, T Kijima, K Azuma, K Kishi… - Japanese journal of …, 2024 - academic.oup.com
Objective As first-line treatment for stage IV or recurrent non-small cell lung cancer,
combination immunotherapy with nivolumab and ipilimumab, with or without chemotherapy …

The Relative risk of immune-related liver dysfunction of PD-1/PD-L1 inhibitors versus chemotherapy in solid tumors: a meta-analysis of randomized controlled trials

S Deng, Q Yang, X Shu, J Lang, S Lu - Frontiers in pharmacology, 2019 - frontiersin.org
Background: Immune checkpoint inhibitors (ICIs) have made a significant breakthrough in
the treatment of solid tumors; however, their use also generates unique immune-related …

Combination of the EP and Anti‐PD‐1 Pathway or Anti‐CTLA‐4 for the Phase III Trial of Small‐Cell Lung Cancer: A Meta‐Analysis

AAA Abunasser, J Xue, EJA Balawi… - Journal of Oncology, 2021 - Wiley Online Library
The morbidity and mortality of lung cancer remain one of the highest among multiple
cancers, respectively. Small‐Cell Lung Cancer (SCLC) accounts for around 10%–15% of all …