Ferroptosis is a newly discovered form of regulated cell death dependent on iron and
reactive oxygen species (ROS). It directly or indirectly affects the activity of glutathione …

The glutathione (GSH) system is considered to be one of the most powerful endogenous
antioxidant systems in the cardiovascular system due to its key contribution to detoxifying …

Ferroptosis is a new form of regulated cell death depending on elevated iron (Fe2+) and
lipid peroxidation levels. Myocardial ischemia/reperfusion (I/R) injury has been shown to be …

Ferroptosis is a nonapoptotic form of cell death characterized by iron‐dependent
accumulation of lipid hydroperoxides to lethal levels. Necroptosis, an alternative form of …

Ferroptosis, first proposed in 2012, is an iron-dependent form of regulated cell death
characterized by excessive polyunsaturated fatty acid oxidation. In the past decade …

Ischemia-reperfusion (I/R) injury is a major challenge in perioperative medicine that
contributes to pathological damage in various conditions, including ischemic stroke …

Myocardial infarction (MI) is a coronary artery-related disease and ranks as the leading
cause of sudden death globally. Resveratrol (Res) is a bioactive component and has …

Context Ferroptosis was described as an important contributor to the myocardial
ischaemia/reperfusion (MIR) injury, and britanin (Bri) was reported to exert antitumor and …

Ferroptosis is an iron‐dependent form of cell death caused by the inactivation of glutathione
peroxidase 4 (GPX4) and accumulation of lipid peroxides. Ferroptosis has been found to …

The mechanism of cardiovascular diseases (CVDs) is complex and threatens human health.
Cardiomyocyte death is an important participant in the pathophysiological basis of CVDs …