The maternal gut microbiome in pregnancy: implications for the developing immune system

O Koren, L Konnikova, P Brodin, IU Mysorekar… - Nature Reviews …, 2024 - nature.com
The gut microbiome has important roles in host metabolism and immunity, and microbial
dysbiosis affects human physiology and health. Maternal immunity and microbial …

Evidence for maternal diet-mediated effects on the offspring microbiome and immunity: implications for public health initiatives

J Mirpuri - Pediatric research, 2021 - nature.com
Diets rich in saturated fats have become a staple globally. Fifty percent of women of
childbearing age in the United States are obese or overweight, with diet being a significant …

A soluble fiber diet increases Bacteroides fragilis group abundance and immunoglobulin A production in the gut

A Nakajima, T Sasaki, K Itoh, T Kitahara… - Applied and …, 2020 - Am Soc Microbiol
Immunoglobulin A (IgA) is essential for defense of the intestinal mucosa against harmful
pathogens. Previous studies have shown that Bacteroidetes, the major phylum of gut …

Placental Epigenome Impacts Fetal Development: Effects of Maternal Nutrients and Gut Microbiota

S Basak, R Mallick, B Navya Sree, AK Duttaroy - Nutrients, 2024 - mdpi.com
Evidence is emerging on the role of maternal diet, gut microbiota, and other lifestyle factors
in establishing lifelong health and disease, which are determined by transgenerationally …

The influence of maternal diet on offspring's gut microbiota in early life

LH Peng, Y Tan, O Bajinka - Archives of Gynecology and Obstetrics, 2024 - Springer
Background The influence of maternal diet on offspring's health is an area of study that is
linked to epigenetics. Maternal diet contributes to determining the health status of offspring …

[HTML][HTML] Maternal dietary fiber intake during pregnancy and child development: the Japan environment and children's study

K Miyake, S Horiuchi, R Shinohara, M Kushima… - Frontiers in …, 2023 - frontiersin.org
Background: Animal studies have shown that maternal low-fiber diets during pregnancy may
impair brain development and function in offspring, but this has not been validated by …

Bioderived materials that disarm the gut mucosal immune system: potential lessons from commensal microbiota

R Harriman, JS Lewis - Acta Biomaterialia, 2021 - Elsevier
Over the course of evolution, mammals and gut commensal microbes have adapted to
coexist with each other. This homeostatic coexistence is dependent on an intricate balance …

Role of Synbiotics in Reproductive Disorders

R Thapa, RM Gilhotra, AA Bhat, M Purohit… - Synbiotics in Human …, 2024 - Springer
It has been discovered that the reproductive tract contains microbial communities, and this
stable microbiome contributes to the preservation of health. Probiotics have been suggested …

[HTML][HTML] Nicotine oral administration attenuates DSS-induced colitis through upregulation of indole in the distal colon and rectum in mice

A Nakajima, T Shibuya, T Sasaki, YJ Lu… - Frontiers in …, 2021 - frontiersin.org
Nicotine affects the gastrointestinal environment and modulates ulcerative colitis (UC).
However, the associations among nicotine, gut metabolites, and UC are still largely …

Three main short-chain fatty acids inhibit the activation of THP-1 cells by Mycoplasma pneumoniae

X Wen, D Xiaoyue, D Longkun, X Yue… - Bioscience …, 2021 - academic.oup.com
The overactivation of macrophages causes chronic inflammatory diseases. Short-chain fatty
acids (SCFAs), potential drugs for clinical treatment, are modulators of macrophage …