Neovascularization plays a substantial role in the invasiveness and metastasis of gastric
cancer. However, the molecular mechanism underlying the control of neovascularization of …

Background Infantile hemangioma (IH) is a common vascular tumor in female infants, which
can lead to aesthetic issues and facial scarring. This study aimed to investigate the inhibitory …

Aim To show that depletion of pancreatic macrophages impairs gestational beta cell
proliferation and leads to glucose intolerance. Materials and Methods Genetic animal …

Cisplatin is a commonly used chemotherapy drug for prostate cancer (PC). However, some
PCs are resistant to cisplatin treatment, while the molecular mechanisms underlying the …

The mechanisms underlying the effects of exocrine dysfunction on the development of
diabetes remain largely unknown. Here we show that pancreatic depletion of SMAD7 …

Background/Aims: Diabetes and Alzheimer's disease are often associated with each other,
whereas the relationship between two diseases is ill-defined. Although hyperglycemia …

Objective Pancreatic beta cells proliferate in response to metabolic requirements during
pregnancy, while failure of this response may cause gestational diabetes. A member of the …

Background: Obesity and insulin resistance lead to islet hyperplasia. However, how the islet
remodeling influences the pancreatic environment and the associated neurovascular …

Background/Aims: The aggressive manner of ovarian cancer (OVC) cells accounts for the
majority of its lethality. Recently, we have shown that placental growth factor (PLGF) …

Neovascularization is critical for the invasion and metastasis of non-small cell lung cancer
(NSCLC). However, the molecular mechanism underlying the control of neovascularization …