Since the publication of the first genome-wide association study for cancer in 2007,
thousands of common alleles that are associated with the risk of cancer have been …

Objective The objective of the French Urology Association Cancer Committee is to propose
an update of the recommendations for the diagnosis and management of prostate cancer …

Although similar phenotypically, there is evidence that male and female breast cancer differ
in their molecular landscapes. In this systematic review, we consolidated all existing …

Purpose We aimed to investigate to what extent polygenic risk scores (PRS), rare
pathogenic germline variants (PVs), and family history jointly influence breast cancer and …

Abstract Background An important fraction (>/~ 10%) of men with high‐risk, localized
prostate cancer and metastatic prostate cancer carry germline (heritable) pathogenic and …

PURPOSE Prostate cancer (PCa) is highly heritable. No validated PCa risk model currently
exists. We therefore sought to develop a genetic risk model that can provide personalized …

Simple Summary Male breast cancer (MBC) is a rare disease. Genetic factors predispose to
male breast cancer. Germline and/or genetic and/or epigenetic alterations at the somatic …

Simple Summary Male breast cancer (mBC) is a rare disease associated with a high
prevalence of pathogenic germline variants (PVs) in the BRCA2 gene. However, data …

The vast majority of new prostate cancer diagnoses are low-grade tumors that are monitored
by active surveillance rather than undergoing immediate treatment. However, a subset of …

Most criteria for genetic testing for prostate cancer susceptibility require a prior diagnosis of
prostate cancer, in particular cases with metastatic disease are selected. Advances in the …