The past, present, and future of antibiotics

MA Cook, GD Wright - Science translational medicine, 2022 - science.org
Antibiotics have transformed modern medicine. They are essential for treating infectious
diseases and enable vital therapies and procedures. However, despite this success, their …

Potential for maternally administered vaccine for infant group B streptococcus

SA Madhi, AS Anderson, J Absalon… - … England Journal of …, 2023 - Mass Medical Soc
Background Natural history studies have correlated serotype-specific anti–capsular
polysaccharide (CPS) IgG in newborns with a reduced risk of group B streptococcal disease …

Spatial distribution, pollution characteristics, and health risks of antibiotic resistance genes in China: a review

Z Xu, Y Jia, B Huang, D Zhao, X Long, S Hu… - Environmental …, 2023 - Springer
With the extensive production and use of antibiotics for medicinal and veterinary purposes,
antibiotics and genes that code for antibiotic resistance are now present in various …

Maternal colonization versus nosocomial transmission as the source of drug-resistant bloodstream infection in an Indian neonatal intensive care unit: a prospective …

ML Robinson, J Johnson, S Naik, S Patil… - Clinical Infectious …, 2023 - academic.oup.com
Background Drug-resistant gram-negative (GN) pathogens are a common cause of neonatal
sepsis in low-and middle-income countries. Identifying GN transmission patterns is vital to …

Vaccine development for bacterial pathogens: Advances, challenges and prospects

IE Mba, HC Sharndama… - Tropical Medicine & …, 2023 - Wiley Online Library
The advent and use of antimicrobials have played a key role in treating potentially life‐
threatening infectious diseases, improving health, and saving the lives of millions of people …

Occurrence, fate, and risk of the organic pollutants of the surface water watch List in European groundwaters: a review

A Jurado, E Pujades, M Walther… - Environmental Chemistry …, 2022 - Springer
Groundwater is the main source of freshwater in the European Union, yet freshwaters are
polluted by organic contaminants if contaminants are not efficiently removed in wastewater …

Available evidence and potential for vaccines for reduction in antibiotic prescriptions

G Gabutti - Human Vaccines & Immunotherapeutics, 2022 - Taylor & Francis
Bacterial antibiotic resistance is a public health issue. It means that drugs become
ineffective, infections persist and have a huge impact on the health of patients and their …

Acute otitis media in children—challenges of antibiotic resistance in the post-vaccination era

C Gavrilovici, EL Spoială, IC Miron, IM Stârcea… - Microorganisms, 2022 - mdpi.com
Acute otitis media (AOM) is a leading cause of antibiotic prescriptions in children worldwide,
even in the era of pneumococcal conjugate vaccines. We aimed to assess the bacterial …

Vaccination is an integral strategy to combat antimicrobial resistance

LP Mullins, E Mason, K Winter, M Sadarangani - PLoS Pathogens, 2023 - journals.plos.org
Antimicrobial-resistant bacterial infections pose a significant challenge to health worldwide.
In 2019, there were an estimated 1.95 million deaths and 47.9 million lost disability-adjusted …

Antibiotic Potentiation as a Promising Strategy to Combat Macrolide Resistance in Bacterial Pathogens

D Paul, M Chawla, T Ahrodia, L Narendrakumar, B Das - Antibiotics, 2023 - mdpi.com
Antibiotics, which hit the market with astounding impact, were once called miracle drugs, as
these were considered the ultimate cure for infectious diseases in the mid-20th century …