To date, the involvement of various genetic markers in the aetiopathogenesis of non-
syndromic orofacial cleft (nsOFC) has been extensively studied. In the present study, we …

Cleft lip and cleft palate (CL/P) are among the most common congenital malformations in
neonates and have syndromic or nonsyndromic forms. Nonsyndromic forms of malformation …

Tooth agenesis is one of the most common dental anomalies, with a complex and not yet
fully elucidated aetiology. Given the crucial role of the Wnt signalling pathway during tooth …

Orofacial clefts (OFCs) are congenital dysmorphologies of the human face and oral cavity,
with a global incidence of 1 per 700 live births. These anomalies exhibit a multifactorial …

Purpose The aim of this study was to use the TaqMan OpenArray system to evaluate
associations between 39 genes and the etiology of nonsyndromic cleft lip and palate …

Palate development is shaped by multiple molecular signaling pathways, including the Wnt
pathway. In mice and humans, mutations in both the canonical and noncanonical arms of …

Objective: Nonsyndromic cleft lip with or without cleft palate (NSCL±P) is a common
craniofacial anomaly with multifactorial etiology. Evidence suggests that variations in WNT …

Background Epidemiological studies have indicated a higher incidence of breast and gastric
cancer in patients with nonsyndromic cleft lip with or without cleft palate (NSCL±P) and their …

Non-syndromic cleft lip with or without palate (NSCL/P) is a common congenital
malformation worldwide, with complex etiology. It has been proposed that interaction of …

Colorectal cancer (CRC) is the third most common cancer and the second leading cause of
death worldwide. The named “destruction complex” has a critical function in the Wnt/β …