Soft fiber electronics based on semiconducting polymer

F Sun, H Jiang, H Wang, Y Zhong, Y Xu, Y Xing… - Chemical …, 2023 - ACS Publications
Fibers, originating from nature and mastered by human, have woven their way throughout
the entire history of human civilization. Recent developments in semiconducting polymer …

A brief history of human disease genetics

M Claussnitzer, JH Cho, R Collins, NJ Cox… - Nature, 2020 - nature.com
A primary goal of human genetics is to identify DNA sequence variants that influence
biomedical traits, particularly those related to the onset and progression of human disease …

Therapeutics data commons: Machine learning datasets and tasks for drug discovery and development

K Huang, T Fu, W Gao, Y Zhao, Y Roohani… - arXiv preprint arXiv …, 2021 - arxiv.org
Therapeutics machine learning is an emerging field with incredible opportunities for
innovatiaon and impact. However, advancement in this field requires formulation of …

[HTML][HTML] Evaluation and mitigation of racial bias in clinical machine learning models: scoping review

J Huang, G Galal, M Etemadi… - JMIR Medical …, 2022 - medinform.jmir.org
Background Racial bias is a key concern regarding the development, validation, and
implementation of machine learning (ML) models in clinical settings. Despite the potential of …

[HTML][HTML] Genomic data in the All of Us research program

Biobank, Mayo Blegen Ashley L. 18 Wirkus Samantha … - Nature, 2024 - nature.com
Comprehensively mapping the genetic basis of human disease across diverse individuals is
a long-standing goal for the field of human genetics,,–. The All of Us Research Program is a …

[HTML][HTML] Precision medicine: disease subtyping and tailored treatment

RC Wang, Z Wang - Cancers, 2023 - mdpi.com
Simple Summary The genomics-based concept of precision medicine began to emerge
following the completion of the Human Genome Project. In contrast to evidence-based …

[HTML][HTML] The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals

Y Cao, L Li, M Xu, Z Feng, X Sun, J Lu, Y Xu, P Du… - Cell research, 2020 - nature.com
Metabolic diseases are the most common and rapidly growing health issues worldwide. The
massive population-based human genetics is crucial for the precise prevention and …

Calibrated prediction intervals for polygenic scores across diverse contexts

K Hou, Z Xu, Y Ding, R Mandla, Z Shi, K Boulier… - Nature Genetics, 2024 - nature.com
Polygenic scores (PGS) have emerged as the tool of choice for genomic prediction in a wide
range of fields. We show that PGS performance varies broadly across contexts and …

[HTML][HTML] Flow cytometry: the next revolution

JP Robinson, R Ostafe, SN Iyengar, B Rajwa, R Fischer - Cells, 2023 - mdpi.com
Unmasking the subtleties of the immune system requires both a comprehensive knowledge
base and the ability to interrogate that system with intimate sensitivity. That task, to a …

[HTML][HTML] The need for a human pangenome reference sequence

KH Miga, T Wang - Annual Review of Genomics and Human …, 2021 - annualreviews.org
The reference human genome sequence is inarguably the most important and widely used
resource in the fields of human genetics and genomics. It has transformed the conduct of …